A potential new treatment method for melanoma skin cancer

Researchers at the National University of Singapore’s Yong Loo Lin School of Medicine (NUS Medicine) have discovered a small man-made molecule that can activate a receptor in the cell membrane to “kill” tumour cells in melanoma skin cancer, controlling the growth of the cancer cells. This process is activated once the molecule is injected into the body. The small molecule NSC49652 will bind to a death receptor p75NTR in the cell membrane, starting a process which then causes melanoma cells to die.

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Making hearing checks easy and accessible for seniors

An NUS-led research initiative is under way to develop and trial accessible and cost-effective hearing services for the elderly in Singapore. It is part of a three-year project which seeks to address the increasing need for hearing care services of the growing elderly population.

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Scientists reveal mystery of superbug evolution

Scientists have found a new way in which bacteria evolve, one they believe is at least 1,000 times more efficient than any currently known mechanism. The insights will help scientists to better understand how dangerous bacteria can rapidly evolve and become increasingly virulent and antibiotic resistant.

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Students compete in search for innovative healthcare ideas

Over the past year, the students from the NUS Yong Loo Lin School of Medicine (NUS Medicine) and their counterparts from the Business, Computing, Engineering, Dentistry, and Science faculties have gone through interdisciplinary boot camps to develop and refine their proposed solutions and prototypes to a number of healthcare problems. The students, grouped into 14 teams, are taking part in the second edition of the Medical Grand Challenge, which was launched last year.

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Neighbourhood Health Service to screen for all chronic illnesses

Singapore’s pioneering student-led health screening programme for residents of rental HDB apartments is going big this year, the 12th since the programme began in 2007. The NUS Medicine student planners of the Neighbourhood Health Service intend to screen residents in Kampong Glam and Queenstown (Leng Kee) for all chronic illnesses as well as oral, vision and hearing health.

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Stronger chemotherapy for children with high-risk leukaemia boosts cure, reduces relapse rates

A team of doctors from Singapore and Malaysia has managed to raise cure rates for a group of child leukemia patients from 69.6 per cent to 91.6 per cent while also lowering relapses from 30 per cent to 13 per cent.

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Key to artery health lies in LYVE-1 Macrophage

A team of NUS Medicine researchers led by Associate Professor Veronique Angeli has identified a population of cells called macrophages that coat the outer walls of healthy arteries and express a protein called LYVE-1. The researchers found that when these cells were absent, arteries accumulate collagen and lose their elasticity, becoming stiff and inflexible.

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