Medical Sciences Cluster

Inspiring Science For Health


The risk of heat stress could increase as heat waves become more common due to climate change. Associate Professor Jason Lee from NUS Medicine’s Department of Physiology provides insights into the effects of humidity on the human body in Channel NewsAsia series: Why It Matters 2. 

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Researchers at the National University of Singapore’s Yong Loo Lin School of Medicine (NUS Medicine) have discovered a small man-made molecule that can activate a receptor in the cell membrane to “kill” tumour cells in melanoma skin cancer, controlling the growth of the cancer cells. This process is activated once the molecule is injected into the body. The small molecule NSC49652 will bind to a death receptor p75NTR in the cell membrane, starting a process which then causes melanoma cells to die. The research team comprises scientists from NUS Department of Physiology, Department of Pharmacy and Life Sciences Institute, University of Calgary’s Cunming School of Medicine, as well as University of Virginia’s Department of Chemical Engineering.

Scientists have found a new way in which bacteria evolve, one they believe is at least 1,000 times more efficient than any currently known mechanism. The insights will help scientists to better understand how dangerous bacteria can rapidly evolve and become increasingly virulent and antibiotic resistant.

Assistant Professor John Chen from the Department of Microbiology and Immunology at the Yong Loo Lin School of Medicine (NUS Medicine) said “Phages are by far the most abundant biological entities on the planet, and the importance of genetic transduction as one of the principle drivers of microbial evolution has never been more apparent than with the discovery of lateral transduction.”

We would like to extend our heartiest congratulations to Associate Professor Lim Kah Leong for receiving the 2018 President’s Science Award! This is the highest accolade for top research scientists and engineers for their outstanding contributions to the scientific community in Singapore. Associate Prof Lim is part of a quartet studying Parkinson’s Disease, where they had successfully created the world’s first live human midbrain in a laboratory. The award winning team consists of Professor Tan Eng King and Associate Professor Louis Tan Chew Seng from the National Neuroscience Institute (NNI) and Professor Ng Huck Hui from the Genome Institute of Singapore (GIS).

At the inaugural Medical Sciences Cluster (MSC) Day, held on 15th August, 2018 we welcomed back more than 200 academics, administrative and laboratory staff to celebrate the beginning of a new academic year. The day started with a short meeting in the CRC auditorium, followed by lunch and a concurrent exhibition by the various platforms (core facilities) in the ground level in MD6.

People are and will always be our greatest asset. At this year’s NUS Medicine Awards, we celebrated our colleagues from the Medical Sciences Cluster who received recognition for their long service and outstanding contributions towards education and research.


The NUS Medicine Postdoctoral Association was officially launched on 20th July 2018 commemorating a milestone for School. The primary objectives of forming this association are to establish a comprehensive professional development framework, foster friendships and encourage collaborations among the postdoctoral fellows.

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