Research Our People

Our People

Our researchers solve biomedical problems and help improve patients’ lives through innovative and translational research.

Research Our Infrastructure

Our Infrastructure

Our sophisticated biomedical research facilities are designed to encourage and enable cutting-edge transformative research.

Research Our Programmes

Our Programmes

Our research programmes have reflected collaboration and productivity. This achievement will be propelled by our flagship Summit Research Programmes. 

NUS Medicine Research
Faculty

Faculty

Fuelling these research programmes is our deep talent base, which is the result of a long-term plan to attract the best and most innovative scientists from around the world. As part of the National University Health System (NUHS) – an academic health centre that includes the National University Hospital – we combine a strong foundation in the basic sciences with the capacity to translate findings to the clinic and beyond.

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Research Programmes

Research Programmes

NUS Medicine fosters collaborative research in various programmes to drive and focus on bench-to-bedside-to-community translation of basic biomedical discoveries. Comprehensive investigations in the following programmes extend from the basic discovery to the development of new approaches towards preventing, diagnosing and treating diseases.

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High Impact Research Stories

High Impact Research Stories

Our researchers solve biomedical problems and help improve patients’ lives through innovative and translational research.

The stories here reflect our sustained and evolving research pursuit; and celebrate the range, depth and the journey that the researchers have undertaken and how it impacts on society, on a national and international level.

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Infrastructure

Infrastructure

Several research facilities have been established to support clinical and translational research. The core facilities also support innovative research at NUS Medicine by providing highly specialised services and staff, and cutting-edge technology.

Biosafety Level 3 Laboratory (BSL-3)
Confocal Microscopy Unit
Electron Microscopy Unit
Flow Cytometry Laboratory
Centre for Translational Research and Diagnostics (CTRAD)
Centre for Health Services and Policy Research (CHSPR)
Medical Engineering and Research Commercialization Initiative (MERCI)
Tissue Repository
Clinical Imaging Research Centre (CIRC)
Clinical Nutrition Research Centre Singapore (CNRC)
Investigational Medicine Unit (IMU) Centre for Personalized and Precision Health (CPPH) Tissue Engineering and Cellular Therapy (TECT)
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Summit Research Programmes

Summit Research Programmes

The Summit Research Programmes (SRPs) bring together established high-caliber investigators to form distinctive collaborative research programmes with high international impact. The SRPs will nurture early-career scientists to produce the next generation of biomedical researchers. The aim is to achieve significant improvements in disease understanding and clinical practice and innovations that will improve health outcomes and lead to societal and economic benefits for Singapore.

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Our Stories

Research at NUS Medicine is as varied and vibrant as our researchers. By combining knowledge gleaned from scientific inquiry with strong clinical expertise, we are improving healthcare for patients in Singapore and beyond. These are just a few stories showing the impact of our research.

Running Against Resistance: The SPRINT-TB Research Programme

This passage could have described many people suffering from tuberculosis (TB) up to the 1940s, when the antibiotic streptomycin was discovered. Despite more TB drugs being available today, TB remains a leading cause of death from infection. This is mostly because of the long and inefficient courses of treatment that are hard to administer and difficult for patients to stick to.

New Hybrid Drug Plugs the Hole in Malaria Drug Resistance

A combination of artemisinin and another drug (artemisinin combination therapy, ACT) is currently the best malaria treatment recommended by the World Health Organization. In early 2015, artemisinin-resistant malaria was confirmed in five countries in Southeast Asia: Cambodia, Laos, Myanmar, Thailand, and Vietnam.

New Genetic Test Helps Doctors Adjust Dose of Potentially Toxic Drug in Asian Patients

Agnes (not her real name) is a typical 7-year-old in Primary 1, except for one thing: she has acute lymphoblastic leukaemia (ALL). She is also extremely sensitive to the common ALL drug 6-mercaptopurine (6-MP) and its toxic side effects. Shortly after starting treatment with 6-MP, Agnes’ blood cell levels plunged, making her susceptible to repeated infections.

Finding New Genes Linked to Glaucoma, the Leading Cause of Permanent Blindness

All over the world, glaucoma is a serious disease that can lead to irreversible blindness. In Singapore, it causes 60% of adult blindness in the Chinese population. Now, several large collaborations anchored by NUS Medicine researchers are helping to figure out the genes involved in this potentially devastating disease.

Nuclear DNA Gets Cut and Activates Immune System to Attack Cancer Cells

The conventional wisdom about cancer cells is that they are masters of camouflage, invisible to the immune system.