Leilei Chen

Chen Leilei

  • Assistant Professor, Department of Anatomy
Administrative Appointment(s)
  • Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Academic Qualifications
  • PhD, The University of Hong Kong, China
  • MD, Jiangsu University, China
Research Interest(s)
  • RNA Editing
  • Post-transcriptional Regulation
  • Cancer Biology
Recent Publications
  • 1. Shigeyasu, K., Okugawa, Y., Toden, S., Miyoshi, J., Toiyama, Y., Nagasaka, T., . . . Goel, A. (2018). AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer.. JCI Insight, 3(12). doi:10.1172/jci.insight.99976.
  • 2. Hong, H., An, O., Chan, T. H. M., Ng, V. H. E., Kwok, H. S., Lin, J. S., . . . Chen, L. (2018). Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer.. Nucleic Acids Res. doi:10.1093/nar/gky396.
  • 3. Ali, A., Levantini, E., Teo, J. T., Goggi, J., Clohessy, J. G., Wu, C. S., . . . Tenen, D. G. (2018). Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer. EMBO MOLECULAR MEDICINE, 10(3), 19 pages. doi:10.15252/emmm.201708313.
  • 4. Dai, Y., Liu, L., Zeng, T., Liang, J. Z., Song, Y., Chen, K., . . . Guan, X. Y. (2018). Overexpression of MUC13, a Poor Prognostic Predictor, Promotes Cell Growth by Activating Wnt Signaling in Hepatocellular Carcinoma. American Journal of Pathology, 188(2), 378-391. doi:10.1016/j.ajpath.2017.10.016.
  • 5. Chow, R. K. K., Tsz-Kwan Sin, S., Liu, M., Li, Y., Man Chan, T. H., Song, Y., . . . Guan, X. -Y. (2017). AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways.. Oncotarget, 8(48), 83469-83479. doi:10.18632/oncotarget.12726.