Juan Pablo Bifani

Bifani Juan Pablo

Appointment(s)
  • Associate Professor, Department of Microbiology & Immunology
Joint Appointment(s)
  • Associate Professor, The London School of Hygiene and Tropical Medicine (LSHTM), Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London WC1E 7HT, United Kingdom
  • Principal Investigator, Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore
Academic Qualifications
  • PhD., New York University, NY, USA
  • MSc., (Biochemistry), Mahidol University, Thailand
  • BSc., University of Guelph, Canada
Research Interest(s)
  • Infectious Diseases
  • Tuberculosis
  • Malaria
  • Klebsiella
  • Drug Resistance
  • Drug Discovery
Recent Publications
  • 1. Dembele L, Gupta DK, Lim MY, Ang X, Selva JJ, Chotivanich K, Nguon C, Dondorp AM, Bonamy GMC, Diagana TT, Bifani P. 2018. Imidazolopiperazines (IPZ) kill both rings and dormant rings in wild type and K13 artemisinin resistant Plasmodium falciparum in vitro. Antimicrobial Agents Chemotherapy pii: AAC.02235-17.
  • 2. Varakorn Kosaisavee, Rossarin Suwanarusk, Adeline C. Y. Chua, Dennis E. Kyle, Benoit Malleret, Rou Zhang, Mallika Imwong, Rawiwan Imerbsin, Ratawan Ubalee, Hugo Samano, Bryan Yeung9, Jessica Ong, Eric Lombardini, François Nosten, Kevin S. W. Tan, Pablo Bifani, Georges Snounou, Laurent Rénia, Bruce Russell. 2017. Species-specific Tropism for Erythrocyte Invasion as an Impediment to Plasmodium cynomolgi’s Zoonotic Potential. Blood- BLOOD. 14;130(11):1357-1363.
  • 3. Dembele L, Ang X, Chavchich M, Bonamy GMC, Selva JJ, Lim MY, Bodenreider C,Yeung BKS, Nosten F, Russell BM, Edstein MD, Straimer J, Fidock DA, Diagana TT, Bifani P. 2017. The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. Sci Rep. 7(1):2325.
  • 4. Lim, M. Y. X., LaMonte, G., Lee, M. C. S., Reimer, C., Tan, B. H., Corey, V., Tjahjadi, B. F., Chua, A., Nachon, M., Wintjens, R., Gedeck, P., Malleret, B., Renia, L., Bonamy, G. M. C., Ho, P. C. L., Yeung, B. K. S., Chow, E. D., Lim, L., Fidock, D. A., Diagana, T. T., Winzeler, E. A., and Bifani, P. 2016. UDP-galactose and Acetyl-CoA transporters as Plasmodium multidrug resistance genes. Nature Microbiology 1:161-66.
  • 5. LaMonte, G., Lim, M. Y. X., Wree, M., Nachon, M., Corey, V., Gedeck, P., Plouffe, D., Du, A., Figueroa, N., Yeung, B. K. S., Bifani*, P., and Winzeler*, E. 2016. Mutations in the P. falciparum Cyclic Amine Resistance Locus (PfCARL) confer multi-drug resistance. mBio 7, e00696-00616.