Wan Jin Hong

Hong Wan Jin

  • Professor, Department of Biochemistry
Administrative Appointment(s)
  • Supervisor, NUS Graduate School for Integrative Sciences and Engineering
Joint Appointment(s)
  • Executive Director, Institute of Molecular and Cellular Biology, A*STAR
  • Editor-in-Chief, Bioscience Reports
  • Member, American Society of Cell Biology
  • Member, American Society for Biochemistry and Molecular Biology
  • Member, American Association for Cancer Research
  • Member, The International Molecular Biology Network
  • Member, Tan Kah Kee International Society and the Chinese Biological Investigators Society
Academic Qualifications
  • PhD, State University of New York, Buffalo, USA
  • BSc, Xiamen University, China
Research Interest(s)
  • Protein Trafficking
  • Cancer Cell Biology
Recent Publications
  • 1. Kaan HYK, Chan SW, Tan SKJ, Guo F, Lim CJ, Hong W, Song H. 2017 May. Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex. Scientific Reports. 7:2035. doi:10.1038/s41598-017-02219-9.
  • 2. Chakraborty S, Njah K, Pobbati AV, Lim YB, Raju A, Lakshmanan M, Tergaonkar V, Lim CT, Hong W. 2017 Mar. Agrin as a Mechanotransduction Signal Regulating YAP through the Hippo Pathway. Cell Reports. 18(10):2464-2479. doi:10.1016/j.celrep.2017.02.041.
  • 3. Liu T, Li H, Hong W, Han W. 2016 Dec. Brefeldin A-inhibited guanine nucleotide exchange protein 3 is localized in lysosomes and regulates GABA signaling in hippocampal neurons. Journal of Neurochemistry. 139(5):748-756. doi:10.1111/jnc.13859.
  • 4. Tan YW, Ang MJY, Lau QY, Poulsen A, Ng FM, Then SW, Peng J, Hill J, Hong WJ, Chia CSB et al. 2016 Sep. Antiviral activities of peptide-based covalent inhibitors of the Enterovirus 71 3C protease. Scientific Reports. 6:33663. doi:10.1038/srep33663.
  • 5. Chen J, Rajasekaran M, Xia H, Zhang X, Kong SN, Sekar K, Seshachalam VP, Deivasigamani A, Goh BKP, Ooi LL et al. 2016 Sep. The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/beta-catenin signalling pathway. Gut. 65(9):1522-1534. doi: 10.1136/gutjnl-2015-310625.
  • 6. Juan WC, Hong W. 2016 Sep. Targeting the Hippo signaling pathway for tissue regeneration and cancer therapy. Genes. 7(9). doi: 10.3390/genes7090055.