Yoshiaki Ito

Ito Yoshiaki

Appointment(s)
  • Professor, Department of Medicine
  • Senior Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Joint Appointment(s)
  • Adjunct Professor, Institute of Molecular and Cell Biology, A*STAR
Academic Qualifications
  • PhD, Tohoku University Graduate School of Medical Sciences, Sendai, Japan
  • MD, Tohoku University, School of Medicine, Sendai, Japan
Research Interest(s)
  • Gastric Cancer
  • RUNX
  • Tumor Suppressor
  • Stem Cells
  • DNA Repair
Recent Publications
  • 1. Krishnan V, Chong YL, Tan TZ, Kulkarni M, Bin Rahmat MB, Tay LS, Sankar H, Jokhun DS, Ganesan A, Chuang LSH et al. 2018 Jan. TGFβ promotes genomic instability after loss of RUNX3. Cancer Research. 78(1):88-102. doi: 10.1158/0008-5472.CAN-17-1178.
  • 2. Selvarajan V, Osato M, Nah GSS, Yan J, Chung T-H, Voon DC-C, Ito Y, Ham MF, Salto-Tellez M, Shimizu N et al.2017 Oct. RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC. Leukemia. 31(10):2219-2227. doi: 10.1038/leu.2017.40.
  • 3. Ebina-Shibuya R, Matsumoto M, Kuwahara M, Jang KJ, Sugai M, Ito Y, Funayama R, Nakayama K, Sato Y, Ishii N et al. 2017 Jan. Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis. Journal of Biological Chemistry. 292(44):18098-18112. doi: 10.1074/jbc.M117.808535.
  • 4. Chuang LSH, Ito K, Ito Y. 2017 Jan. Roles of RUNX in solid tumors. Adv Exp Med Biol. 962:299-320. doi: 10.1007/978-981-10-3233-2_19.
  • 5. Krishnan V, Ito Y. 2017 Jan. A regulatory role for RUNX1, RUNX3 in the maintenance of genomic integrity. Adv Exp Med Biol. 962:491-510. doi: 10.1007/978-981-10-3233-2_29.