Daniel G. Tenen

Tenen Daniel G.

Appointment(s)
  • Distinguished Professor, Department of Medicine
Administrative Appointment(s)
  • Director, Cancer Science Institute of Singapore, National University of Singapore
Academic Qualifications
  • MD, Harvard Medical School, USA
Research Interest(s)
  • Transcription Factors
  • Gene Regulation
  • Leukaemia
  • Lung Cancer
  • Liver Cancer
Recent Publications
  • 1. Ye M, Zhang H, Yang H, Koche R, Staber PB, Cusan M, Levantini E, Welner RS, Bach CS, Zhang J, Krivtsov AV, Armstrong SA, Tenen DG. 2015 Nov. Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia. Cell Stem Cell. 17(5):611-23. doi: 10.1016/j.stem.2015.08.011. 26412561.
  • 2. Li Y, Zhou QL, Sun W, Chandrasekharan P, Cheng HS, Ying Z, Lakshmanan M, Raju A, Tenen DG, Cheng SY, Chuang KH, Li J, Prabhakar S, Li M, Tergaonkar V. 2015 Oct. Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. Nat Cell Biol. 17(10):1327-38. doi: 10.1038/ncb3240. 26389665.
  • 3. Radomska HS, Jernigan F, Nakayama S, Jorge SE, Sun L, Tenen DG, Kobayashi SS. 2015 Oct. A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation. J Biomol Screen. 20(9):1150-9. doi: 10.1177/1087057115592220. 26109609.
  • 4. Giotopoulos G, van der Weyden L, Osaki H, Rust AG, Gallipoli P, Meduri E, Horton SJ, Chan WI, Foster D, Prinjha RK, Pimanda JE, Tenen DG, Vassiliou GS, Koschmieder S, Adams DJ, Huntly BJ. 2015 Sep. A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression. J Exp Med. 212(10):1551-69. doi: 10.1084/jem.20141661. 26304963.
  • 5. Kabiri Z, Numata A, Kawasaki A, Edison, Tenen DG, Virshup DM. 2015 Aug. Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells. Blood. 126(9):1086-94. doi: 10.1182/blood-2014-09-598540. 26089398.