H. Phillip Koeffler

Koeffler H. Phillip

Appointment(s)
  • Professor, Department of Medicine
  • Senior Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Administrative Appointment(s)
  • Deputy Director (Research), National University Cancer Institute, Singapore, National University Health System
Joint Appointment(s)
  • Professor, Department of Medicine, Cedars-Sinai Professorial Series
  • Professor of Bioengineering, University of California, Los Angeles, USA
  • Professor in Residence Above Scale, University of California, Los Angeles, USA
Academic Qualifications
  • MD, Baylor College of Medicine, USA
  • BA, University of Wisconsin, USA
Research Interest(s)
  • Sequencing
  • Superenhancers
  • RNA Splicing
Recent Publications
  • 1. Guan DX, Shi J, Zhang Y, Zhao JS, Long LY, Chen TW, Zhang EB, Feng YY, Bao WD, Deng YZ, Qiu L, Zhang XL, Koeffler HP, Cheng SQ, Li JJ, Xie D. 2015 Dec. Sorafenib enriches epithelial cell adhesion molecule-positive tumor initiating cells and exacerbates a subtype of hepatocellular carcinoma through TSC2-AKT cascade. Hepatology. 62(6):1791-803. doi: 10.1002/hep.28117. 26257239.
  • 2. Kanojia D, Nagata Y, Garg M, Lee DH, Sato A, Yoshida K, Sato Y, Sanada M, Mayakonda A, Bartenhagen C, Klein HU, Doan NB, Said JW, Mohith S, Gunasekar S, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Myklebost O, Yang H, Dugas M, Meza-Zepeda LA, Silberman AW, Forscher C, Tyner JW, Ogawa S, Koeffler HP. 2015 Dec. Genomic landscape of liposarcoma. Oncotarget. 6(40):42429-44. doi: 10.18632/oncotarget.6464. 26643872.
  • 3. Garg M, Nagata Y, Kanojia D, Mayakonda A, Yoshida K, Haridas Keloth S, Zang ZJ, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ding LW, Alpermann T, Sun QY, Lin DC, Chien W, Madan V, Liu LZ, Tan KT, Sampath A, Venkatesan S, Inokuchi K, Wakita S, Yamaguchi H, Chng WJ, Kham SK, Yeoh AE, Sanada M, Schiller J, Kreuzer KA, Kornblau SM, Kantarjian HM, Haferlach T, Lill M, Kuo MC, Shih LY, Blau IW, Blau O, Yang H, Ogawa S, Koeffler HP. 2015 Nov. Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse. Blood. 126(22):2491-501. doi: 10.1182/blood-2015-05-646240. 26438511.
  • 4. Sakamoto S, Kawabata H, Masuda T, Uchiyama T, Mizumoto C, Ohmori K, Koeffler HP, Kadowaki N, Takaori-Kondo A. 2015 Oct. H-Ferritin Is Preferentially Incorporated by Human Erythroid Cells through Transferrin Receptor 1 in a Threshold-Dependent Manner. PLoS One. 10(10):e0139915. doi: 10.1371/journal.pone.0139915. 26441243.
  • 5. Zheng Y, Guo J, Zhou J, Lu J, Chen Q, Zhang C, Qing C, Koeffler HP, Tong Y 2015 Aug. FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion. BMC Med Genomics. 8:49. doi: 10.1186/s12920-015-0126-9. 26264222.