Lih Wen Deng

Deng Lih Wen

  • Associate Professor, Department of Biochemistry
Administrative Appointment(s)
  • Faculty, NUS Graduate School for Integrative Sciences and Engineering
  • Affiliate, National University Cancer Institute, Singapore, National University Hospital
Academic Qualifications
  • PhD, University of Cambridge, United Kingdom
  • BSc, National Taiwan University, Taiwan
Research Interest(s)
  • Genomic Instability
  • Cervical Cancer
  • Ovarian Cancer
  • Cancer Metabolism
  • Chemoradiation Resistance
Recent Publications
  • 1. Zhou, P., Ding, X., Wan, X., Liu, L., Yuan, X., Zhang, W., . . . Zhang, Y. (2018). MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation. NATURE COMMUNICATIONS, 9, 13 pages. doi:10.1038/s41467-018-03563-8.
  • 2. Lee, Z. -W., Teo, X. -Y., Song, Z. J., Nin, D. S., Novera, W., Choo, B. A., . . . Deng, L. -W. (2017). Intracellular Hyper-Acidification Potentiated by Hydrogen Sulfide Mediates Invasive and Therapy Resistant Cancer Cell Death. FRONTIERS IN PHARMACOLOGY, 8, 10 pages. doi:10.3389/fphar.2017.00763.
  • 3. Rajagopalan, D., Pandey, A. K., Xiuzhen, M. C., Lee, K. K., Hora, S., Zhang, Y., . . . Jha, S. (2017). TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter. PLOS PATHOGENS, 13(10), 24 pages. doi:10.1371/journal.ppat.1006681.
  • 4. Liang, D., Bian, J., Deng, L. -W., & Huang, D. (2017). Cyclic polysulphide 1,2,4-trithiolane from stinky bean (Parkia speciosa seeds) is a slow releasing hydrogen sulphide (H2S) donor. JOURNAL OF FUNCTIONAL FOODS, 35, 197-204. doi:10.1016/j.jff.2017.05.040.
  • 5. Zhang, X., Novera, W., Zhang, Y., & Deng, L. -W. (2017). MLL5 (KMT2E): structure, function, and clinical relevance. CELLULAR AND MOLECULAR LIFE SCIENCES, 74(13), 2333-2344. doi:10.1007/s00018-017-2470-8.