Lih Wen Deng

Deng Lih Wen

Appointment(s)
  • Associate Professor, Department of Biochemistry
Administrative Appointment(s)
  • Faculty, NUS Graduate School for Integrative Sciences and Engineering
  • Affiliate, National University Cancer Institute, Singapore, National University Health System
Academic Qualifications
  • PhD, University of Cambridge, United Kingdom
  • BSc, National Taiwan University, Taiwan
Research Interest(s)
  • Genomic Instability
  • Cervical Cancer
  • Ovarian Cancer
  • Cancer Metabolism
  • Chemoradiation Resistance
Recent Publications
  • 1. Lee ZW, Teo XY, Song ZJ, Nin DS, Novera W, Choo BA, Dymock BW, Moore PK, Huang RYJ, Deng LW. 2017 Oct. Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death. Frontiers in Pharmacology. 8(OCT). doi: 10.3389/fphar.2017.00763.
  • 2. Rajagopalan D, Pandey AK, Xiuzhen MC, Lee KK, Hora S, Zhang Y, Chua BH, Kwok HS, Bhatia SS, Deng LW et al. 2017 Oct. TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter. PLoS Pathogens. 13(10):e1006681. doi: 10.1371/journal.ppat.1006681.
  • 3. Liang D, Bian J, Deng L-W, Huang D. 2017 Aug. Cyclic polysulphide 1,2,4-trithiolane from stinky bean (Parkia speciosa seeds) is a slow releasing hydrogen sulphide (H2S) donor. Journal of Functional Foods. 35:197-204. doi: 10.1016/j.jff.2017.05.040.
  • 4. Zhang X, Novera W, Zhang Y, Deng LW. 2017 Jul. MLL5 (KMT2E): structure, function, and clinical relevance. Cellular and Molecular Life Sciences. 74(13):2333-2344. doi: 10.1007/s00018-017-2470-8.
  • 5. Feng W, Novera W, Peh K, Neo D, Ramanujulu PM, Moore PK, Deng LW, Dymock BW. 2017 Jan. Discovery of medium ring thiophosphorus based heterocycles as antiproliferative agents. Bioorganic and Medicinal Chemistry Letters. 27(4):967-972. doi: 10.1016/j.bmcl.2016.12.079.