Paul A MacAry

MacAry Paul A

Appointment(s)
  • Associate Professor, Department of Microbiology and Immunology
Administrative Appointment(s)
  • Director, Life Sciences Institute (LSI)
  • Director LSI Antibody Engineering Programme
Joint Appointment(s)
  • Co-chair CREATE-NUS-HUJ Inflammation Research Programme
Academic Qualifications
  • PhD, University of London, United Kingdom
  • BSc (Hons), Glasgow University,¬†United Kingdom
Research Interest(s)
  • Antibody Technology
  • Infectious Diseases
Recent Publications
  • 1. Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.Gu Y, Wong YH, Liew CW, Chan CEZ, Murali TM, Yap J, Too CT, Purushotorman K, Hamidinia M, El Sahili A, Goh ATH, Teo RZC, Wood KJ, Hanson BJ, Gascoigne NRJ, Lescar J, Vathsala A, MacAry PA. Nat Commun. 2019 Feb 21;10(1):893. doi: 10.1038/s41467-019-08790-1.
  • 2. Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. Zhao X, Sankaran S, Yap J, Too CT, Ho ZZ, Dolton G, Legut M, Ren EC, Sewell AK, Bertoletti A, MacAry PA, Brzostek J, Gascoigne NRJ. Nat Commun. 2018 Jul 13;9(1):2716. doi: 10.1038/s41467-018-05288-0. PMID: 30006605
  • 3. Molecular engineering of a therapeutic antibody for Blo t 5-induced allergic asthma. Chan JHS, Chua YL, Peh HY, Jovanovic V, Gascoigne NRJ, Wong WSF, Chew FT, Hanson BJ, Kemeny DM, MacAry PA. J Allergy Clin Immunol. 2017 May;139(5):1705-1708.e6. doi: 10.1016/j.jaci.2016.10.028. Epub 2016 Dec 5. PMID:27923562
  • 4. Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificities. Lai J, Tan WJ, Too CT, Choo JA, Wong LH, Mustafa FB, Srinivasan N, Lim AP, Zhong Y, Gascoigne NR, Hanson BJ, Chan SH, Chen J, MacAry PA. Blood. 2016 Sep 8;128(10):1396-407. doi: 10.1182/blood-2016-03-707836. Epub 2016 Jun 23. PMID:27338099
  • 5. Virus-specific T lymphocytes home to the skin during natural dengue infection. Rivino L, Kumaran EA, Thein TL, Too CT, Gan VC, Hanson BJ, Wilder-Smith A, Bertoletti A, Gascoigne NR, Lye DC, Leo YS, Akbar AN, Kemeny DM, MacAry PA. Sci Transl Med. 2015 Mar 11;7(278):278ra35. doi: 10.1126/scitranslmed.aaa0526. PMID: 25761891