Yoshiaki Ito

Ito Yoshiaki

  • Professor, Department of Medicine
  • Senior Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Joint Appointment(s)
  • Adjunct Professor, Institute of Molecular and Cell Biology, A*STAR
Academic Qualifications
  • PhD, Tohoku University Graduate School of Medical Sciences, Sendai, Japan
  • MD, Tohoku University, School of Medicine, Sendai, Japan
Research Interest(s)
  • Gastric Cancer
  • RUNX
  • Tumor Suppressor
  • Stem Cells
  • DNA Repair
Recent Publications
  • 1. Voon DC, Hor YT, Ito Y. 2015 Dec. The RUNX complex: reaching beyond haematopoiesis into immunity. Immunology. 146(4):523-36. doi: 10.1111/imm.12535. 26399680.
  • 2. Lee KG, Kim SS, Kui L, Voon DC, Mauduit M, Bist P, Bi X, Pereira NA, Liu C, Sukumaran B, Rénia L, Ito Y, Lam KP. 2015 Feb. Bruton’s Tyrosine Kinase Phosphorylates DDX41 and Activates its Binding of dsDNA and STING to Initiate Type 1 Interferon Response. Cell Rep. 10(7):1055-65. doi: 10.1016/j.celrep.2015.01.039. 25704810.
  • 3. Ito Y, Bae SC, Chuang LS. 2015 Feb. The RUNX family: developmental regulators in cancer. Nat Rev Cancer. 15(2):81-95. doi: 10.1038/nrc3877. 25592647.
  • 4. Wang CQ, Krishnan V, Tay LS, Chin DW, Koh CP, Chooi JY, Nah GS, Du L, Jacob B, Yamashita N, Lai SK, Tan TZ, Mori S, Tanuichi I, Tergaonkar V, Ito Y, Osato M. 2014 Aug. Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects. Cell Rep. 8(3):767-82. doi: 10.1016/j.celrep.2014.06.046. 25066130.
  • 5. Hor YT, Voon DC, Koo JK, Wang H, Lau WM, Ashktorab H, Chan SL, Ito Y. 2014 Jul. A role for RUNX3 in inflammation-induced expression of IL23A in gastric epithelial cells. Cell Rep. 8(1):50-8. doi: 10.1016/j.celrep.2014.06.003. 25008775.