Justin Chu

Chu Justin

  • Assistant Professor, Department of Microbiology and Immunology
Joint Appointment(s)
  • Principal Investigator, Collaborative and Translation Unit for HFMD, Institute of  Molecular and Cell Biology, A*STAR
Academic Qualifications
  • PhD (Molecular Virology), National University of Singapore, Singapore
  • BSc (Hons, First Class), National University of Singapore, Singapore
Research Interest(s)
  • Virology
  • Antivirals
  • Hand, Foot and Mouth Disease
  • Dengue Virus
  • Chikungunya Virus
  • Vaccine
Recent Publications
  • 1. Morchang A, Lee RCH, Yenchitsomanus PT, Sreekanth GP, Noisakran S, Chu JJH, Limjindaporn T. 2017 Nov. RNAi screen reveals a role of SPHK2 in dengue virus–mediated apoptosis in hepatic cell lines. PLoS ONE. 12(11). doi: 10.1371/journal.pone.0188121.
  • 2. Mirza SB, Lee RCH, Chu JJH, Salmas RE, Mavromoustakos T, Durdagi S. 2017 Oct. Discovery of selective dengue virus inhibitors using combination of molecular fingerprint-based virtual screening protocols, structure-based pharmacophore model development, molecular dynamics simulations and in vitro studies. Journal of Molecular Graphics and Modelling. 77:338. doi: 10.1016/j.jmgm.2017.08.006.
  • 3. Wu KX, Chu JJH. 2017 Jul. Antiviral screen identifies EV71 inhibitors and reveals camptothecin-target, DNA topoisomerase 1 as a novel EV71 host factor. Antiviral Research. 143:122-133. doi: 10.1016/j.antiviral.2017.04.008.
  • 4. Reyes M, Piotrowski M, Ang SK, Chan J, He S, Chu JJH, Kah JCY. 2017 May. Exploiting the Anti-Aggregation of Gold Nanostars for Rapid Detection of Hand, Foot, and Mouth Disease Causing Enterovirus 71 Using Surface-Enhanced Raman Spectroscopy. Analytical Chemistry. 89(10):5373-5381. doi: 10.1021/acs.analchem.7b00066.
  • 5. Gunaseelan S, Chu JJH. 2017 Apr. Identifying novel antiviral targets against enterovirus 71: where are we?. Future Virology. 12(4):171-191. doi: 10.2217/fvl-2016-0144.