Daniel G. Tenen

Tenen Daniel G.

Appointment(s)
  • Distinguished Professor, Department of Medicine
Administrative Appointment(s)
  • Director, Cancer Science Institute of Singapore, National University of Singapore
Academic Qualifications
  • MD, Harvard Medical School, USA
Research Interest(s)
  • Transcription Factors
  • Gene Regulation
  • Leukaemia
  • Lung Cancer
  • Liver Cancer
Recent Publications
  • 1. Liu, B. H., Jobichen, C., Chia, C. S. B., Chan, T. H. M., Tang, J. P., Chung, T. X. Y., . . . Tenen, D. G. (2018). Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1801253115.
  • 2. Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., . . . Nimer, S. D. (2018). CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis. Cancer Cell, 33(6), 1111-1127.e5. doi:10.1016/j.ccell.2018.05.007.
  • 3. Numata, A., Kwok, H. S., Kawasaki, A., Li, J., Zhou, Q. -L., Kerry, J., . . . Tenen, D. G. (2018). The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia. NATURE COMMUNICATIONS, 9, 16 pages. doi:10.1038/s41467-018-03854-0.
  • 4. Cusan, M., Cai, S. F., Mohammad, H. P., Krivtsov, A., Chramiec, A., Loizou, E., . . . Armstrong, S. A. (2018). LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1-and C/EBP alpha-dependent enhancers in AML. BLOOD, 131(15), 1730-1742. doi:10.1182/blood-2017-09-807024.
  • 5. Thi Ngoc, P. C., Tan, S. H., Tan, T. K., Chan, M. M., Li, Z., Yeoh, A. E. J., . . . Sanda, T. (2018). Identification of novel lncRNAs regulated by the TAL1 complex in T-cell acute lymphoblastic leukemia. Leukemia, 1-14. doi:10.1038/s41375-018-0110-4.