Daniel G. Tenen

Tenen Daniel G.

Appointment(s)
  • Distinguished Professor, Department of Medicine
Administrative Appointment(s)
  • Director, Cancer Science Institute of Singapore, National University of Singapore
Academic Qualifications
  • MD, Harvard Medical School, USA
Research Interest(s)
  • Transcription Factors
  • Gene Regulation
  • Leukaemia
  • Lung Cancer
  • Liver Cancer
Recent Publications
  • 1. Gonzalez D, Luyten A, Bartholdy B, Zhou Q, Kardosova M, Ebralidze A, Swanson KD, Radomska HS, Zhang P, Kobayashi SS et al. 2017 Nov. ZNF143 protein is an important regulator of the myeloid transcription factor C/EBP. Journal of Biological Chemistry. 292(46):18924-18936. doi: 10.1074/jbc.M117.811109.
  • 2. Pulikkan JA, Tenen DG, Behre G. 2017 Nov. C/EBP alpha deregulation as a paradigm for leukemogenesis. Leukemia. 31(11):2279-2285. doi: 10.1038/leu.2017.229.
  • 3. Tamura A, Hirai H, Yokota A, Kamio N, Sato A, Shoji T, Kashiwagi T, Torikoshi Y, Miura Y, Tenen DG et al. 2017 Oct. C/EBP beta is required for survival of Ly6C(-) monocytes. Blood. 130(16):1809-1818. doi: 10.1182/blood-2017-03-772962.
  • 4. Qi L, Song Y, Chan THM, Yang H, Lin CH, Tay DJT, Hong H, Tang SJ, Tan KT, Huang XX et al. 2017 Oct. An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer. Nucleic Acids Research. 45(18):10436-10451. doi: 10.1093/nar/gkx667.
  • 5. Rajagopalan D, Pandey AK, Xiuzhen MC, Lee KK, Hora S, Zhang Y, Chua BH, Kwok HS, Bhatia SS, Deng LW et al. 2017 Oct. TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter. PLoS Pathogens. 13(10):e1006681. doi: 10.1371/journal.ppat.1006681.