Kah Leong Lim

Lim Kah Leong

Appointment(s)
  • Associate Professor, Department of Physiology
Administrative Appointment(s)
  • Head, Deparment of Physiology, NUS Yong Loo Lin School of Medicine
  • Visiting Lead, Strategic Research Alliances, National Neuroscience Institute
Academic Qualifications
  • PhD, Institute of Molecular and Cell Biology, A*STAR
Research Interest(s)
  • Parkinson's disease: mechanisms, models, marker & therapy
Recent Publications
  • 1. Tan, K. K. B., Lim, W. W. M., Chai, C., Kukumberg, M., Lim, K. L., Goh, E. L. K., & Yim, E. K. F. (2018). Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells. SCIENTIFIC REPORTS, 8, 13 pages. doi:10.1038/s41598-018-27653-1.
  • 2. Wang, L., Cho, Y. L., Tang, Y., Wang, J., Park, J. E., Wu, Y., . . . Shen, H. M. (2018). PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy. Cell Research, 1-16. doi:10.1038/s41422-018-0056-0.
  • 3. Baek, J. S., Tee, J. K., Pang, Y. Y., Tan, E. Y., Lim, K. L., Ho, H. K., & Loo, S. C. J. (2018). Improved Bioavailability of Levodopa Using Floatable Spray-Coated Microcapsules for the Management of Parkinson’s Disease. NeuroMolecular Medicine, 20(2), 262-270. doi:10.1007/s12017-018-8491-0.
  • 4. Shao, Y. -M., Ma, X., Paira, P., Tan, A., Herr, D. R., Lim, K. L., . . . Pastorin, G. (2018). Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A(2A) and dopamine D-2 receptors for Parkinson's disease treatment. PLOS ONE, 13(1), 27 pages. doi:10.1371/journal.pone.0188212.
  • 5. Liu, C., Zhang, C. -W., Zhou, Y., Wong, W. Q., Lee, L. C., Ong, W. Y., . . . Dawe, G. S. (2018). APP upregulation contributes to retinal ganglion cell degeneration via JNK3. CELL DEATH AND DIFFERENTIATION, 25(4), 661-676. doi:10.1038/s41418-017-0005-3.
  • 6. Xiao, B., Deng, X., Lim, G. G. Y., Xie, S., Zhou, Z. D., Lim, K. L., & Tan, E. K. (2017). Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria. Cell Death and Disease, 8(10). doi:10.1038/cddis.2017.463.