Wen Shan Yew

Yew Wen Shan

  • Associate Professor, Department of Biochemistry
Administrative Appointment(s)
  • Supervisor, NUS Graduate School for Integrative Sciences and Engineering
  • Principal Investigator, Synthetic Biology for Clinical and Technological Innovation, National University of Singapore
  • Technical Member, Singapore Consortium for Synthetic Biology
  • Deputy Chair, Masters in Environmental Management PMC
Academic Qualifications
  • PhD, University of Illinois at Urbana-Champaign, USA
  • MS, University of Illinois at Urbana-Champaign, USA
  • BSc, National University of Singapore, Singapore
Research Interest(s)
  • Synthetic Enzymology
  • Synthetic Biology
  • Enzyme Engineering
  • Drug Design and Development
  • Environmental Sustainability
Recent Publications
  • 1. Go MK, Chow JY, Yew WS. 2018 Jan. Directed evolution of quorum-quenching enzymes: A method for the construction of a directed evolution platform and characterization of a quorum-quenching lactonase from geobacillus kaustophilus. Methods Mol Biol. 1673:311-323. doi: 10.1007/978-1-4939-7309-5_24.
  • 2. Pham HL, Wong A, Chua N, Teo WS, Yew WS, Chang MW. 2017 Sep. Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-tolerant phenotypes. Nature Communications. 8:411. doi: 10.1038/s41467-017-00511-w.
  • 3. Hwang IY, Koh E, Kim HR, Yew WS, Chang MW. 2016 Jul. Reprogrammable microbial cell-based therapeutics against antibiotic-resistant bacteria. Drug Resistance Updates. 27:59-71. doi: 10.1016/j.drup.2016.06.002.
  • 4. Lim YP, Go MK, Yew WS. 2016 Jun. Exploiting the Biosynthetic Potential of Type III Polyketide Synthases. Molecules. 21(6):806. doi: 10.3390/molecules21060806.
  • 5. Tay SB, Chow JY, Go MK, Yew WS. 2016 Jan. Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases. Journal of Visualized Experiments. e53243. doi: 10.3791/53243.