Xin-Yuan Fu

Fu Xin-Yuan

  • Professor, Department of Biochemistry, NUS Yong Loo Lin School of Medicine
  • Professor, Department of Biological Sciences, National University of Singapore
Administrative Appointment(s)
  • Director, International Relations (China), NUS Yong Loo Lin School of Medicine
  • Supervisor, NUS Graduate School for Integrated Sciences and Engineering
  • Senior Principal Investigator, Cancer Stem Cells Programme, Cancer Science Institute of Singapore, National University of Singapore
Academic Qualifications
  • Postdoctoral Training, Rockefeller University, USA
  • PhD, Columbia University, USA
Research Interest(s)
  • STAT3
  • Stem Cells
  • Tumorigenesis
  • Epigenetic
  • Tumor
Recent Publications
  • 1. Gu, H., Do, D. V., Liu, X., Xu, L., Su, Y., Nah, J. M., . . . Fu, X. Y. (2018). The STAT3 Target Mettl8 Regulates Mouse ESC Differentiation via Inhibiting the JNK Pathway. Stem Cell Reports, 10(6), 1807-1820. doi:10.1016/j.stemcr.2018.03.022.
  • 2. Liu, C., Zhang, C. -W., Zhou, Y., Wong, W. Q., Lee, L. C., Ong, W. Y., . . . Dawe, G. S. (2018). APP upregulation contributes to retinal ganglion cell degeneration via JNK3. CELL DEATH AND DIFFERENTIATION, 25(4), 661-676. doi:10.1038/s41418-017-0005-3.
  • 3. Xu, L., Liu, X., Sheng, N., Oo, K. S., Liang, J., Chionh, Y. H., . . . Fu, X. Y. (2017). Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans. Journal of Biological Chemistry, 292(35), 14695-14703. doi:10.1074/jbc.M117.798298.
  • 4. Zhang, W., Qu, X., Chen, B., Snyder, M., Wang, M., Li, B., . . . Shou, W. (2016). Critical roles of STAT3 in β-adrenergic functions in the heart. Circulation, 133(1), 48-61. doi:10.1161/CIRCULATIONAHA.115.017472.
  • 5. Kumar, A., Lualdi, M., Lyozin, G. T., Sharma, P., Loncarek, J., Fu, X. -Y., & Kuehn, M. R. (2015). Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration. DEVELOPMENTAL BIOLOGY, 400(1), 1-9. doi:10.1016/j.ydbio.2014.12.016.