Ee Sin Chen

Chen Ee Sin

  • Assistant Professor, Department of Biochemistry
Administrative Appointment(s)
  • Supervisor, NUS Graduate School for Integrative Sciences and Engineering
Joint Appointment(s)
  • Editorial Board, Scientific Reports
  • Associate Editor, Gene
Academic Qualifications
  • PhD, Kyoto University, Japan
  • MSc, Kyoto University, Japan
  • BSc (Hons), National University of Singapore, Singapore
Research Interest(s)
  • Cancer
  • Epigenetics
  • Chromatin
  • Chemogenomics
  • Chemotherapeutic Drugs
  • Cell Cycle
Recent Publications
  • 1. Chen, E. S. (2018). Targeting epigenetics using synthetic lethality in precision medicine.. Cell Mol Life Sci. doi:10.1007/s00018-018-2866-0.
  • 2. Seah, K. S., Loh, J. Y., Nguyen, T. T. T., Tan, H. L., Hutchinson, P. E., Lim, K. K., . . . Chen, E. S. (2018). SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling. Experimental Cell Research. doi:10.1016/j.yexcr.2018.06.029.
  • 3. Tan, H. L., Lim, K. K., Yang, Q., Fan, J. S., Sayed, A. M. M., Low, L. S., . . . Chen, E. S. (2018). Prolyl isomerization of the CENP-A N-Terminus regulates centromeric integrity in fission yeast. Nucleic Acids Research, 46(3), 1167-1179. doi:10.1093/nar/gkx1180.
  • 4. Ren, B., Tan, H. L., Nguyen, T. T. T., Sayed, A. M. M., Li, Y., Mok, Y. K., . . . Chen, E. S. (2018). Regulation of transcriptional silencing and chromodomain protein localization at centromeric Heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast. Nucleic Acids Research, 46(1), 189-202. doi:10.1093/nar/gkx1010.
  • 5. Lee, S. Q. E., Tan, T. S., Kawamukai, M., & Chen, E. S. (2017). Cellular factories for coenzyme Q10production. Microbial Cell Factories, 16(1). doi:10.1186/s12934-017-0646-4.