Ee Sin Chen

Chen Ee Sin

  • Assistant Professor, Department of Biochemistry
Administrative Appointment(s)
  • Supervisor, NUS Graduate School for Integrative Sciences and Engineering
Joint Appointment(s)
  • Editorial Board, Scientific Reports
  • Associate Editor, Gene
Academic Qualifications
  • PhD, Kyoto University, Japan
  • MSc, Kyoto University, Japan
  • BSc (Hons), National University of Singapore, Singapore
Research Interest(s)
  • Cancer
  • Epigenetics
  • Chromatin
  • Chemogenomics
  • Chemotherapeutic Drugs
  • Cell Cycle
Recent Publications
  • 1. Ren B, Tan HL, Nguyen TTT, Sayed AMM, Li Y, Mok YK, Yang H, Chen ES. 2018 Jan. Regulation of transcriptional silencing and chromodomain protein localization at centromeric heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast. Nucleic Acids Res. 46(1):189-202. doi: 10.1093/nar/gkx1010.
  • 2. Tan HL, Lim KK, Yang Q, Fan JS, Sayed AMM, Low LS, Ren B, Lim TK, Lin Q, Mok YK et al. 2017 Nov. Prolyl isomerization of the CENP-A N-terminus regulates centromeric integrity in fission yeast. Nucleic Acids Res. doi: 10.1093/nar/gkx1180.
  • 3. Lee SQE, Tan TS, Kawamukai M, Chen ES. 2017 Mar. Cellular factories for coenzyme Q10 production. Microbial Cell Factories. 16(1). doi: 10.1186/s12934-017-0646-4.
  • 4. Jackson RA, Nguyen ML, Barrett AN, Tan YY, Choolani MA, Chen ES. 2016 Nov. Synthetic combinations of missense polymorphic genetic changes underlying Down syndrome susceptibility. Cellular and Molecular Life Sciences. 73(21):4001-4017. doi: 10.1007/s00018-016-2276-0.
  • 5. Jackson RA, Chen ES. 2016 Jun. Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs. Pharmacology and Therapeutics. 162:69-85. doi: 10.1016/j.pharmthera.2016.01.014.