H. Phillip Koeffler

Koeffler H. Phillip

  • Professor, Department of Medicine
  • Senior Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Administrative Appointment(s)
  • Deputy Director (Research), National University Cancer Institute, Singapore, National University Health System
Joint Appointment(s)
  • Professor, Department of Medicine, Cedars-Sinai Professorial Series
  • Professor of Bioengineering, University of California, Los Angeles, USA
  • Professor in Residence Above Scale, University of California, Los Angeles, USA
Academic Qualifications
  • MD, Baylor College of Medicine, USA
  • BA, University of Wisconsin, USA
Research Interest(s)
  • Sequencing
  • Superenhancers
  • RNA Splicing
Recent Publications
  • 1. Gugliotta G, Sudo M, Cao Q, Lin DC, Sun H, Takao S, Le Moigne R, Rolfe M, Gery S, Muschen M et al. 2017 Oct. Valosin-Containing Protein/p97 as a Novel Therapeutic Target in Acute Lymphoblastic Leukemia. Neoplasia. 19(10):750-761. doi: 10.1016/j.neo.2017.08.001.
  • 2. Garg M, Kanojia D, Mayakonda A, Ganesan TS, Sadhanandhan B, Suresh S, Sneha S, Nagare RP, Said JW, Doan NB et al. 2017 Sep. Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin. Scientific Reports. 7:9749. doi: 10.1038/s41598-017-10325-x.
  • 3. Sun H, Lin DC, Cao Q, Pang B, Gae DD, Lee VKM, Lim HJ, Doan N, Said JW, Gery S et al. 2017 Aug. Identification of a Novel SYK/c-MYC/MALAT1 Signaling Pathway and Its Potential Therapeutic Value in Ewing Sarcoma. Clinical Cancer Research. 23(15):4376-4387. doi: 10.1158/1078-0432.CCR-16-2185.
  • 4. Lin DC, Mayakonda A, Dinh HQ, Huang P, Lin L, Liu X, Ding LW, Wang J, Berman BP, Song EW et al. 2017 May. Genomic and Epigenomic Heterogeneity of Hepatocellular Carcinoma. Cancer Research. 77(9):2255-2265. doi: 10.1158/0008-5472.CAN-16-2822.
  • 5. Ding LW, Sun QY, Mayakonda A, Tan KT, Chien W, Lin DC, Jiang YY, Xu L, Garg M, Lao ZT et al. 2017 Mar. Mutational profiling of acute lymphoblastic leukemia with testicular relapse. Journal of Hematology abd Oncology. 10:65. doi: 10.1186/s13045-017-0434-y.