H. Phillip Koeffler

Koeffler H. Phillip

Appointment(s)
  • Professor, Department of Medicine
  • Senior Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Administrative Appointment(s)
  • Deputy Director (Research), National University Cancer Institute, Singapore, National University Health System
Joint Appointment(s)
  • Professor, Department of Medicine, Cedars-Sinai Professorial Series
  • Professor of Bioengineering, University of California, Los Angeles, USA
  • Professor in Residence Above Scale, University of California, Los Angeles, USA
Academic Qualifications
  • MD, Baylor College of Medicine, USA
  • BA, University of Wisconsin, USA
Research Interest(s)
  • Sequencing
  • Superenhancers
  • RNA Splicing
Recent Publications
  • 1. Zhao, Z., Jia, Q., Wu, M. S., Xie, X., Wang, Y., Song, G., . . . Shen, J. (2018). Degalactotigonin, a natural compound from Solanum nigrum L., inhibits growth and metastasis of osteosarcoma through GSK3β inactivation-mediated repression of the Hedgehog/gli1 pathway. Clinical Cancer Research, 24(1), 130-144. doi:10.1158/1078-0432.CCR-17-0692.
  • 2. Huang, M., Chen, Y., Yang, M., Guo, A., Xu, Y., Xu, L., & Koeffler, H. P. (2018). dbCoRC: a database of core transcriptional regulatory circuitries modeled by H3K27ac ChIP-seq signals. NUCLEIC ACIDS RESEARCH, 46(D1), D71-D77. doi:10.1093/nar/gkx796.
  • 3. Yuan, J., Jiang, Y. -Y., Mayakonda, A., Huang, M., Ding, L. -W., Lin, H., . . . Koeffler, H. P. (2017). Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma. CANCER RESEARCH, 77(23), 6614-6626. doi:10.1158/0008-5472.CAN-17-1143.
  • 4. Lin, D. -C., & Koeffler, H. P. (2017). Genomic lesions drive the metastasis of esophageal squamous cell carcinoma. JOURNAL OF THORACIC DISEASE, 9(10), 3523-3524. doi:10.21037/jtd.2017.09.58.
  • 5. Gugliotta, G., Sudo, M., Cao, Q., Lin, D. -C., Sun, H., Takao, S., . . . Koeffler, H. P. (2017). Valosin-Containing Protein/p97 as a Novel Therapeutic Target in Acute Lymphoblastic Leukemia. NEOPLASIA, 19(10), 750-761. doi:10.1016/j.neo.2017.08.001.