Sern Yan, Nicholas Chew

Chew Sern Yan, Nicholas

  • Assistant Professor, Department of ┬áMedicine
  • Senior Consultant, Division of Infectious Disease, Department of Medicine, National University Hospital
Administrative Appointment(s)
  • Member, Graduate Programme Committee, NUS Yong Loo Lin School of Medicine
  • Member, NUS BSL-3 Biosafety Committee
Academic Qualifications
  • MB
  • BCH
  • BAO
  • PhD
  • MRCP
  • Dip GUM
Research Interest(s)
  • Bone Metabolism
  • HIV
  • Bone Strength
  • Osteoporosis
  • Mesenchymal Stem Cells
  • Osteoblast
  • Osteoclast
Recent Publications
  • 1. Li, L., Lim, R. Z. L., Lee, L. S. U., & Chew, N. S. Y. (2018). HIV glycoprotein gp120 enhances mesenchymal stem cell migration by upregulating CXCR4 expression. Biochimica et Biophysica Acta - General Subjects, 1862(8), 1790-1800. doi:10.1016/j.bbagen.2018.05.001
  • 2. Lim, R. Z. L., Li, L., Yong, E. L., & Chew, N. (2018). STAT-3 regulation of CXCR4 is necessary for the prenylflavonoid Icaritin to enhance mesenchymal stem cell proliferation, migration and osteogenic differentiation. Biochimica et Biophysica Acta - General Subjects, 1862(7), 1680-1692. doi:10.1016/j.bbagen.2018.04.016
  • 3. Puthucheary, Z. A., Sun, Y., Zeng, K., Vu, L. H., Zhang, Z. W., Lim, R. Z. L., . . . Cove, M. E. (2017). Sepsis Reduces Bone Strength Before Morphologic Changes Are Identifiable. CRITICAL CARE MEDICINE, 45(12), e1254-e1261. doi:10.1097/CCM.0000000000002732
  • 4. Lim, R. Z. L., Li, L., Chew, N., & Yong, E. L. (2017). The prenylflavonoid Icaritin enhances osteoblast proliferation and function by signal transducer and activator of transcription factor 3 (STAT-3) regulation of C-X-C chemokine receptor type 4 (CXCR4) expression. Bone, 105, 122-133. doi:10.1016/j.bone.2017.08.028
  • 5. Tan, E. M., Li, L., Indran, I. R., Chew, N., & Yong, E. -L. (2017). TRAF6 Mediates Suppression of Osteoclastogenesis and Prevention of Ovariectomy-Induced Bone Loss by a Novel Prenylflavonoid. JOURNAL OF BONE AND MINERAL RESEARCH, 32(4), 846-860. doi:10.1002/jbmr.3031