Poh San Lai

Lai Poh San

Appointment(s)
  • Associate Professor, Department of Paediatrics
Administrative Appointment(s)
  • Deputy Chairman, NUS Institutional Biosafety Committee
  • Vice-Chair, MD1 Tahir Foundation Research Safety Commitee
  • Member, NUS Medicine Faculty Safety Committee
  • Member, Centre for Translational Medicine Safety Committee
Joint Appointment(s)
  • Adjunct Faculty, Genome Institute of Singapore, A*STAR
  • Adjunct Principal Member of Technical Staff, Defence Medical Research & Environmental Research Institutes, DSO National Laboratories
  • Member, Defence Science Organisation and Singapore Armed Forces Institutional Review Board
Academic Qualifications
  • PhD, National University of Singapore, Singapore
Research Interest(s)
  • Neuromuscular
  • Congenital
  • Next-gen Sequencing
  • NGS
  • Diagnosis
Recent Publications
  • 1. Krol KM, Monakhov M, Lai PS, Ebstein RP, Grossmann T. 2015 Sep. Genetic variation in CD38 and breastfeeding experience interact to impact infants' attention to social eye cues. Proc Natl Acad Sci U S A. 112(39):E5434-42. doi: 10.1073/pnas.1506352112. 26371313.
  • 2. Ebstein RP, Monakhov MV, Lu Y, Jiang Y, Lai PS, Chew SH. 2015 Aug. Association between the dopamine D4 receptor gene exon III variable number of tandem repeats and political attitudes in female Han Chinese. Proceedings. Proc Biol Sci. 82(1813):20151360. doi: 10.1098/rspb.2015.1360. 26246555.
  • 3. Yamamoto T, Sato H, Lai PS, Nurputra DK, Harahap NI, Morikawa S, Nishimura N, Kurashige T, Ohshita T, Nakajima H, Yamada H, Nishida Y, Toda S, Takanashi J, Takeuchi A, Tohyama Y, Kubo Y, Saito K, Takeshima Y, Matsuo M, Nishio H. 2014 Nov. Intragenic mutations in SMN1 may contribute more significantly to clinical severity than SMN2 copy numbers in some spinal muscular atrophy (SMA) patients. Brain Dev. 36(10):914-20. doi: 10.1016/j.braindev.2013.11.009. 24359787.
  • 4. Seow N, Lai PS, Yung LY. 2014 Jan. Gold nanostructures for the multiplex detection of glucose-6-phosphate dehydrogenase gene mutations. Anal Biochem. 451:56-62. doi: 10.1016/j.ab.2014.01.014. 24491445.
  • 5. Nurputra DK, Lai PS, Harahap NI, Morikawa S, Yamamoto T, Nishimura N, Kubo Y, Takeuchi A, Saito T, Takeshima Y, Tohyama Y, Tay SK, Low PS, Saito K, Nishio H. 2013 Sep. Spinal muscular atrophy: from gene discovery to clinical trials. Ann Hum Genet. 77(5):435-63. doi: 10.1111/ahg.12031. 23879295.