Catherine Ong

Ong Catherine

Appointment(s)
  • Assistant Professor, Department of Medicine
  • Consultant, Division of Infectious Diseases, University Medicine Cluster, National University Health System
Joint Appointment(s)
  • Visiting Consultant, Tuberculosis Control Unit, Tan Tock Seng Hospital, Singapore
Academic Qualifications
  • MBBS, National University of Singapore, Singapore
  • MRCP, Member of Royal College of Physicians, United Kingdom |MMed (Int Med), National University of Singapore, Singapore
  • PhD, Imperial College London, United Kingdom
  • FAMS, Fellow of the Academy Medicine, Singapore
Research Interest(s)
  • Tuberculosis
  • Host-pathogen interactions
  • Biomarker discovery
  • Host-directed therapy
  • Rapid pathogen detection
  • Antimicrobial resistance
Recent Publications
  • 1. KL Chew, DHL Ng, JWP Teo, KB Tan, MLM Poon, PA Tambyah, CWM Ong. Disseminated Volvariella volvacea infections in patients with haematological malignancies: a case-series. Clinical Microbiology and Infection. (IF 5.4) (Manuscript in Press)
  • 2. CWM Ong, K Fox, A Ettorre, P Elkington, JS Friedland Hypoxia increases neutrophil-dependent matrix destruction after exposure to M. tuberculosis. Nature Scientific Reports volume 8, Article number: 11475. (2018) (IF 4.6)
  • 3. S Brilha, CWM Ong, B Weksler, N Romero, P Couraud, and J Friedland. Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impairs blood-brain barrier function in an in vitro culture-based CNS TB model. Nature Scientific Reports 7, Article number: 16031 (2017) doi:10.1038/s41598-017-16250-3. (IF 4.6)
  • 4. CWM Ong, PJ Pabisiak, S Brilha, P Singh, F Roncaroli, PT Elkington, JS Friedland. Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis J Neuroinflammation 2017,14:31. DOI 10.1186/s12974-017-0801-1. (IF 5.1)
  • 5. CWM Ong, P Elkington, S Brilha, C Ugarte-Gil, M Tome-Esteban, LB Tezera, PJ Pabisiak, RC Moores, T Sathyamoorthy, V Patel, RH Gilman, JC Porter, JS Friedland. Neutrophil-derived MMP-8 drives AMPK-dependent matrix destruction in human pulmonary tuberculosis. PLOS Pathogens 2015 May 21;11(5):e1004917. doi: 10.1371/journal.ppat.1004917. eCollection 2015 May. (IF 6.6)