Yi Ann, Louis Chai

Chai Yi Ann, Louis

  • Assistant Professor, Department of Medicine
  • Senior Consultant, Division of Infectious Disease, Department of Medicine, National University Hospital
Joint Appointment(s)
  • Principal Investigator, Opportunistic Infections Group 
Academic Qualifications
  • MBBS, National University of Singapore, Singapore
  • PhD, Maastricht University, The Netherlands
  • MRCP, Royal College of Physicians, United Kingdom
Research Interest(s)
  • Immunocompromised Hosts
  • Fungal Infections
  • Immunology
  • Host Pathogen Interaction
Recent Publications
  • 1. Pang L, Harris PNA, Seiler RL, Ooi PL, Cutter J, Goh KT, Cook AR, Fisher D, Chai LYA. 2018 Jan. Melioidosis, Singapore, 2003-2014. Emerging Infectious Diseases. 24(1):140-143. doi: 10.3201/eid2401.161449.
  • 2. Sam QH, Chang MW, Chai LYA. 2017 Feb. The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host. International Journal of Molecular Sciences. 18(2):330. doi: 10.3390/ijms18020330.
  • 3. Lévy R, Okada S, Béziat V, Moriya K, Liu C, Chai LYA, Migaud M, Hauck F, Al Ali A, Cyrus C et al. 2016 Dec. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency. Proceedings of the National Academy of Sciences. 113(51):E8277-E8285. doi: 10.1073/pnas.1618300114.
  • 4. Tham EH, Huang C-H, Soh JY, Thayalasingam M, Lee AJ, Lum LHW, Poon LM, Lye DCB, Chai LYA, Tambyah PA et al. 2016 Aug. Neutralizing Anti-Interferon-Gamma Autoantibody Levels May Not Correlate With Clinical Course of Disease. Clinical Infectious Diseases. 63(4):572-+(2). doi: 10.1093/cid/ciw351.
  • 5. Zhao YJ, Khoo AL, Tan G, Teng M, Tee C, Tan BH, Ong B, Lim BP, Chai LYA. 2016 Jan. Network Meta-analysis and Pharmacoeconomic Evaluation of Fluconazole, Itraconazole, Posaconazole, and Voriconazole in Invasive Fungal Infection Prophylaxis. Antimicrobial Agents and Chemotherapy. 60(1):376-386. doi: 10.1128/AAC.01985-15.