Sik Yin, Roger Foo

Foo Sik Yin, Roger

Appointment(s)
  • Associate Professor, Department of Medicine
  • Senior Consultant, Division of Cardiology, National University Heart Centre, National University Health System
Joint Appointment(s)
  • Senior Investigator, Genome Institute of Singapore, A*STAR
Academic Qualifications
  • MD, National University of Singapore, Singapore
  • MBBS, National University of Singapore, Singapore
  • FRCP, Royal College of Physicians, United Kingdom
  • FAHA, American Heart Association, USA
Research Interest(s)
  • Molecular Epigenetics
  • Chromatin Organisation
  • Cardiac Genomics and Epigenomics
  • Heart Failure
  • Genetics
Recent Publications
  • 1. Stenzig, J., Schneeberger, Y., Loeser, A., Peters, B. S., Schaefer, A., Zhao, R. -R., . . . Eschenhagen, T. (2018). Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 120, 53-63. doi:10.1016/j.yjmcc.2018.05.012
  • 2. Zhao, R. -R., Ackers-Johnson, M., Stenzig, J., Chen, C., Ding, T., Zhou, Y., . . . Foo, R. S. Y. (2018). Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling.. Circulation, 137(23), 2497-2513. doi:10.1161/CIRCULATIONAHA.117.030353
  • 3. Wang, J., Li, G., Yu, D., Wong, Y. P., Yong, T. F., Liang, M. C., . . . Soong, T. W. (2018). Characterization of CaV1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and CaV1.2 exon 33 expressions in human heart failure.. Channels (Austin), 12(1), 51-57. doi:10.1080/19336950.2017.1381805
  • 4. See, K., Tan, W. L. W., Lim, E. H., Tiang, Z., Lee, L. T., Li, P. Y. Q., . . . Foo, R. S. (2017). Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo. NATURE COMMUNICATIONS, 8, 13 pages. doi:10.1038/s41467-017-00319-8
  • 5. Lia, G., Wang, J., Liao, P., Bartels, P., Zhang, H., Yu, D., . . . Soong, T. W. (2017). Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic. Proceedings of the National Academy of Sciences of the United States of America, 114(21), E4288-E4295. doi:10.1073/pnas.1617205114/-/DCSupplemental