Sik Yin, Roger Foo

Foo Sik Yin, Roger

  • Associate Professor, Department of Medicine
  • Senior Consultant, Division of Cardiology, National University Heart Centre, National University Health System
Joint Appointment(s)
  • Senior Investigator, Genome Institute of Singapore, A*STAR
Academic Qualifications
  • MD, National University of Singapore, Singapore
  • MBBS, National University of Singapore, Singapore
  • FRCP, Royal College of Physicians, United Kingdom
  • FAHA, American Heart Association, USA
Research Interest(s)
  • Molecular Epigenetics
  • Chromatin Organisation
  • Cardiac Genomics and Epigenomics
  • Heart Failure
  • Genetics
Recent Publications
  • 1. Wang J, Li G, Yu D, Wong YP, Yong TF, Liang MC, Liao P, Foo R, Hoppe UC, Soong TW. 2018 Jan. Characterization of CaV1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and CaV1.2 exon 33 expressions in human heart failure. Channels (Austin). 12(1):51-57. doi: 10.1080/19336950.2017.1381805.
  • 2. Suhaimi N-AM, Phyo WM, Yap HY, Choy SHY, Wei X, Choudhury Y, Tan WJ, Tan LAPY, Foo RSY, Tan SHS et al. 2017 Sep. Metformin Inhibits Cellular Proliferation and Bioenergetics in Colorectal Cancer Patient-Derived Xenografts. Molecular Cancer Therapeutics. 16(9):2035-2044. doi: 10.1158/1535-7163.MCT-16-0793.
  • 3. Lim JFY, Zafra M, Mocanu JD, Umareddy I, de Lima Lopes G, Foo R, Jha A, Hickinbotham L. 2017 Sep. Preparing health systems in Southeast and East Asia for new paradigms of care/personalized medicine in cancers: are health systems ready for evolving cancer management?. Journal of Asian Public Policy. 10(3):268-286. doi: 10.1080/17516234.2016.1214433.
  • 4. See K, Tan WLW, Lim EH, Tiang Z, Lee LT, Li PYQ, Luu TDA, Ackers-Johnson M, Foo RS. 2017 Aug. Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo. Nature Communications. 8:225. doi: 10.1038/s41467-017-00319-8.
  • 5. Lia G, Wang J, Liao P, Bartels P, Zhang H, Yu D, Liang MC, Poh KK, Yu CY, Jiang F et al. 2017 May. Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic. Proceedings of the National Academy of Sciences of the United States of America. 114(21):E4288-E4295. doi: 10.1073/pnas.1617205114/-/DCSupplemental.