Kim Peng, Mitchell Lai

Lai Kim Peng, Mitchell

Appointment(s)
  • Assistant Professor, Department of Pharmacology
Administrative Appointment(s)
  • Coordinator, UROPS, Department of Pharmacology                                                
Joint Appointment(s)
  • Visiting Senior Fellow, Wolfson Centre for Age-Related Diseases, Kings College London, United Kingdom
Academic Qualifications
  • PhD, University of Sydney, Australia
  • BSc, University of Alberta, Canada
Research Interest(s)
  • Dementia
  • Neurochemistry
  • Neuropathology |Biomarkers
  • Pathogenesis
Recent Publications
  • 1. Zhou ZD, Xie SP, Sathiyamoorthy S, Saw WT, Sing TY, Ng SH, Chua HP, Tang AM, Shaffra F, Li Z, Wang H, Ho PG, Lai MK, Angeles DC, Lim TM, Tan EK. 2015 Nov. F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy. Hum Mol Genet. 24(22):6314-30. doi: 10.1093/hmg/ddv340. 26310625.
  • 2. Gallart-Palau X, Serra A, Wong AS, Sandin S, Lai MK, Chen CP, Kon OL, Sze SK. 2015 Sep. Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR). Sci Rep. 5:14664. doi: 10.1038/srep14664. 26419333.
  • 3. Howlett DR, Whitfield D, Johnson M, Attems J, O'Brien JT, Aarsland D, Lai MK, Lee JH, Chen C, Ballard C, Hortobágyi T, Francis PT. 2015 Jul. Regional Multiple Pathology Scores are Associated with Cognitive Decline in Lewy Body Dementias. Brain Pathol. 25(4):401-8. doi: 10.1111/bpa.12182. 25103200.
  • 4. Chan SJ, Chai C, Lim TW, Yamamoto M, Lo EH, Lai MK, Wong PT. 2015 Apr. Cystathionine ß-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury. ASN Neuro. 7(2). doi: 10.1177/1759091415578711. 25873304.
  • 5. Mohamed NE1, Lee JH, Francis PT, Esiri MM, Chen CP, Lai MK. 2015. Differential alterations of neocortical GluN receptor subunits in patients with mixed subcortical ischemic vascular dementia and Alzheimer's disease. J Alzheimers Dis. 44(2):431-7. doi: 10.3233/JAD-141764. 25261450.