Shuo-Chien Ling

Ling Shuo-Chien

Appointment(s)
  • Assistant Professor, Department of Physiology, NUS Yong Loo Lin School of Medicine
  • Assistant Professor, Programme in Neuroscience and Behaviour Disorders, Duke-NUS Medical School
Academic Qualifications
  • PhD, University of Illinois at Urbana-Champaign, USA
  • BS (Engineering), National Tsing Hua University, Taiwan
Research Interest(s)
  • Ageing and Neurodegeneration
  • RNA Biology
  • Non-cell-autonomous Contribution
  • Synaptic Plasticity and Injury
  • Protein Homeostasis and Autophagy
Recent Publications
  • 1. Lai SL, Ling SC, Kuo LH, Shu YC, Chow WY, Chang YC. 1998 Oct. Characterization of granular particles isolated from postsynaptic densities. J. Neurochem. 71(4):1694-701. 9751204.
  • 2. Angenstein F, Evans AM, Settlage RE, Moran ST, Ling SC, Klintsova AY, Shabanowitz J, Hunt DF, Greenough WT. 2002 Oct. A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. J Neurosci. 22(20):8827-37. 12388589.
  • 3. Ling SC, Fahrner PS, Greenough WT, Gelfand VI. 2004 Dec. Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. Proc Natl Acad Sci U S A. 101(50):17428-33. doi: 10.1073/pnas.0408114101. 15583137.
  • 4. Kim H, Ling SC, Rogers GC, Kural C, Selvin PR, Rogers SL, Gelfand VI. 2007 Feb. Microtubule binding by dynactin is required for microtubule organization but not cargo transport. J Cell Biol. 176(5):641-51. doi: 10.1083/jcb.200608128. 17325206.
  • 5. Ling SC, Albuquerque CP, Han JS, Lagier-Tourenne C, Tokunaga S, Zhou H, Cleveland DW. 2010 Jul. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proc Natl Acad Sci U S A. 107(30):13318-23. doi: 10.1073/pnas.1008227107. 20624952.