Nicholas Robert John Gascoigne

Gascoigne Nicholas Robert John

Appointment(s)
  • Professor, Department of Microbiology and Immunology
Administrative Appointment(s)
  • Head, Department of Microbiology and Immunology, NUS Yong Loo Lin School of Medicine
Academic Qualifications
  • PhD, University College London, United Kingdom
  • BSc (Hons), Aberystwyth University, United Kingdom
Research Interest(s)
  • Signal Transduction
  • T Cells
  • T Cell Receptor
  • Thymus
  • Imaging
Recent Publications
  • 1. Balyan, R., Brzostek, J., & Gascoigne, N. R. J. (2018). CD8(+) T cells have commitment issues. NATURE IMMUNOLOGY, 19(8), 797-799. doi:10.1038/s41590-018-0169-0.
  • 2. Zhao, X., Sankaran, S., Yap, J., Too, C. T., Ho, Z. Z., Dolton, G., . . . Gascoigne, N. R. J. (2018). Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. NATURE COMMUNICATIONS, 9, 13 pages. doi:10.1038/s41467-018-05288-0.
  • 3. Chen, E. W., Brzostek, J., Gascoigne, N. R. J., & Rybakin, V. (2018). Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation. SCIENTIFIC REPORTS, 8, 9 pages. doi:10.1038/s41598-018-28106-5.
  • 4. Brameshuber, M., Kellner, F., Rossboth, B. K., Ta, H., Alge, K., Sevcsik, E., . . . Huppa, J. B. (2018). Monomeric TCRs drive T cell antigen recognition article. Nature Immunology, 19(5), 487-496. doi:10.1038/s41590-018-0092-4.
  • 5. Gautam, N., Sankaran, S., Yason, J. A., Tan, K. S. W., & Gascoigne, N. R. J. (2018). A high content imaging flow cytometry approach to study mitochondria in T cells: MitoTracker Green FM dye concentration optimization. METHODS, 134, 11-19. doi:10.1016/j.ymeth.2017.11.015.