Nicholas Robert John Gascoigne

Gascoigne Nicholas Robert John

Appointment(s)
  • Professor, Department of Microbiology and Immunology
Administrative Appointment(s)
  • Head, Department of Microbiology and Immunology, NUS Yong Loo Lin School of Medicine
Academic Qualifications
  • PhD, University College London, United Kingdom
  • BSc (Hons), Aberystwyth University, United Kingdom
Research Interest(s)
  • Signal Transduction
  • T Cells
  • T Cell Receptor
  • Thymus
  • Imaging
Recent Publications
  • 1. Tay NQ, Lee DCP, Chua YL, Prabhu N, Gascoigne NRJ, Kemeny DM. 2017 Nov. CD40L Expression Allows CD8(+) T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells. Frontiers in Immunology. 8:1484. doi: 10.3389/fimmu.2017.01484.
  • 2. Lai J, Choo JAL, Tan WJ, Too CT, Oo MZ, Suter MA, Mustafa FB, Srinivasan N, Chan CEZ, Lim AGX et al. 2017 Aug. TCR-like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus-transformed B lymphoblastoid cells expressing different HLA-A*02 microvariants. Scientific Reports. 7:9923. doi: 10.1038/s41598-017-10265-6.
  • 3. Brzostek J, Gascoigne NRJ. 2017 Jul. Thymic Origins of T Cell Receptor Alloreactivity. Transplantation. 101(7):1535-1541. doi: 10.1097/TP.0000000000001654.
  • 4. Chan JHS, Chua YL, Peh HY, Jovanovic V, Gascoigne NRJ, Wong WSF, Chew FT, Hanson BJ, Kemeny DM, MacAry PA. 2017 May. Molecular engineering of a therapeutic antibody for Blo t 5-induced allergic asthma. Journal of Allergy and Clinical Immunology. 139(5):1705-+(10). doi: 10.1016/j.jaci.2016.10.028. |Gautam N, Sankaran S, Yason JA, Tan KSW, Gascoigne NRJ. 2017 Jan. A high content imaging flow cytometry approach to study mitochondria in T cells: MitoTracker Green FM dye concentration optimization. Methods. doi: 10.1016/j.ymeth.2017.11.015.