Matthew Chang

Chang Matthew

  • Associate Professor, Department of Biochemistry
Administrative Appointment(s)
  • Director, Synthetic Biology for Clinical and Technological Innovation, National University of Singapore
  • Lead, Synthetic Biology Summit Research Programme, National University Health System
  • Director, Singapore Consortium for Synthetic Biology
Academic Qualifications
  • PhD, University of Maryland, USA
  • BSc, Seoul National University, Korea
Research Interest(s)
  • Synthetic Biology
  • Microbiome Engineering
  • Metabolic Engineering
  • Engineering Biology
Recent Publications
  • 1. Ho CL, Tan HQ, Chua KJ, Kang A, Lim KH, Ling KL, Yew WS, Lee YS, Thiery JP, Chang MW. 2018 Jan. Engineered commensal microbes for diet-mediated colorectal-cancer chemoprevention. Nature Biomedical Engineering. 2(1):27-37. doi: 10.1038/s41551-017-0181-y.
  • 2. Costello CM, Phillipsen MB, Hartmanis LM, Kwasnica MA, Chen V, Hackam D, Chang MW, Bentley WE, March JC. 2017 Dec. Microscale Bioreactors for in situ characterization of GI epithelial cell physiology. Scientific Reports. 7:12515. doi: 10.1038/s41598-017-12984-2.
  • 3. Pham HL, Ho CL, Wong A, Lee YS, Chang MW. 2017 Dec. Applying the design-build-test paradigm in microbiome engineering. Current Opinion in Biotechnology. 48:85-93. doi: 10.1016/j.copbio.2017.03.021.
  • 4. Li P, Dou X, Müller M, Feng C, Chang MW, Frettlöh M, Schönherr H. 2017 Nov. Autoinducer Sensing Microarrays by Reporter Bacteria Encapsulated in Hybrid Supramolecular-Polysaccharide Hydrogels. Macromolecular Bioscience. 17(11). doi: 10.1002/mabi.201700176.
  • 5. Pham HL, Wong A, Chua N, Teo WS, Yew WS, Chang MW. 2017 Sep. Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-tolerant phenotypes. Nature Communications. 8:411. doi: 10.1038/s41467-017-00511-w.