Shuo-Chien Ling

Ling Shuo-Chien

Appointment(s)
  • Assistant Professor, Department of Physiology, NUS Yong Loo Lin School of Medicine
  • Assistant Professor, Programme in Neuroscience and Behaviour Disorders, Duke-NUS Medical School
Academic Qualifications
  • PhD, University of Illinois at Urbana-Champaign, USA
  • BS (Engineering), National Tsing Hua University, Taiwan
Research Interest(s)
  • Ageing and Neurodegeneration
  • RNA Biology
  • Non-cell-autonomous Contribution
  • Synaptic Plasticity and Injury
  • Protein Homeostasis and Autophagy
Recent Publications
  • 1. Ditsworth D, Maldonado M, McAlonis-Downes M, Sun S, Seelman A, Drenner K, Arnold E, Ling SC, Pizzo D, Ravits J et al. 2017 Jun. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis. Acta Neuropathologica. 133(6):907-922. doi: 10.1007/s00401-017-1698-6.
  • 2. Tio M, Wen R, Lim YL, Wang H, Ling SC, Zhao Y, Tan EK. 2016 Nov. FUS-linked essential tremor associated with motor dysfunction in Drosophila. Human Genetics. 135(11):1223-123. doi: 10.1007/s00439-016-1709-z.
  • 3. Seredenina T, Nayernia Z, Sorce S, Maghzal GJ, Filippova A, Ling SC, Basset O, Plastre O, Daali Y, Rushing EJ et al. 2016 Aug. Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis. Free Radical Biology and Medicine. 97:95-108. doi: 10.1016/j.freeradbiomed.2016.05.016.
  • 4. Jiang J, Zhu Q, Gendron TF, Saberi S, McAlonis-Downes M, Seelman A, Stauffer JE, Jafar-nejad P, Drenner K, Schulte D et al. 2016 May. Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs. Neuron. 90(3):535-550. doi: 10.1016/j.neuron.2016.04.006.