Jia En, John Chua

Chua Jia En, John

  • Assistant Professor, Department of Physiology
Joint Appointment(s)
  • Principal Investigator, Institute for Molecular and Cell Biology, A*STAR
Academic Qualifications
  • Dr. rer. nat., University of Hamburg, Germany
  • MSc, National University of Singapore, Singapore
  • BSc (Honours, Second Upper), National University of Singapore, Singapore
Research Interest(s)
  • Intracellular Trafficking
  • Synapse Biology
  • Developmental Neurobiology
  • Signalling Pathways
  • Proteomics
  • Interactomics
Recent Publications
  • 1. Tan LHR, Tan AJR, Ng YY, Chua JJE, Chew WS, Muralidharan S, Torta F, Dutta B, Sze SK, Herr DR et al. 2017 Oct. Enriched Expression of Neutral Sphingomyelinase 2 in the Striatum is Essential for Regulation of Lipid Raft Content and Motor Coordination. Molecular Neurobiology. 1-16. doi: 10.1007/s12035-017-0784-z.
  • 2. Butkevich E, Härtig W, Nikolov M, Erck C, Grosche J, Urlaub H, Schmidt CF, Klopfenstein DR, Chua JJ. 2016. Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking. Sci Rep. 6:26965. doi: 10.1038/srep26965.
  • 3. Kohansal-Nodehi M, Chua, JJ, Urlaub H, Jahn R, Czernik D. 2016 Apr. Analysis of protein phosphorylation in nerve terminal reveals extensive changes in active zone proteins upon exocytosis. Elife. 26;5. pii: e14530. doi: 10.7554/eLife.14530.
  • 4. Yagensky O, Kalantary Dehaghi T, Chua, JJ. 2016 Feb. The Roles of Microtubule-Based Transport at Presynaptic Nerve Terminals. Front Synaptic Neurosci. 10;8:3. doi: 10.3389/fnsyn.2016.00003.
  • 5. Binotti B, Pavlos NJ, Riedel D, Wenzel D, Vorbrüggen G, Schalk AM, Kühnel K, Boyken J, Erck C, Martens H, Chua JJ, Jahn R. 2015 Feb. The GTPase Rab26 links synaptic vesicles to the autophagy pathway. 4:e05597. doi: 10.7554/eLife.05597.