Shih-Yin Tsai

Tsai Shih-Yin

  • Assistant Professor, Department of Physiology
Academic Qualifications
  • PhD, The Ohio State University, USA
  • BSc, National Yang-Ming University, Taiwan
Research Interest(s)
  • Ageing
  • Sarcopenia
  • Sex-dimorphism
  • Protein homeostasis
  • mTOR
Recent Publications
  • 1. Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G. 2017 Mar. Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. J Clin Invest. 127(3):830-842. doi: 10.1172/JCI87583.
  • 2. Tsai SY, Rodriguez AA, Dastidar SG, Del Greco E, Carr KL, Sitzmann JM, Academia EC, Viray CM, Martinez LL, Kaplowitz BS, Ashe TD, La Spada AR, Kennedy BK. 2016 Aug. Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice. Cell Rep.16(7):1903-14. doi: 10.1016/j.celrep.2016.07.029.
  • 3. Julian LM, Liu Y, Pakenham CA, Dugal-Tessier D, Ruzhynsky V, Bae S, Tsai SY, Leone G, Slack RS, Blais A. 2016 Apr. Tissue-specific targeting of cell fate regulatory genes by E2f factors. Cell Death Differ. 23(4):565-75. doi: 10.1038/cdd.2015.36.
  • 4. Tsai SY, Sitzmann JM, Dastidar SG, Rodriguez AA, Vu SL, McDonald CE, Academia EC, O'Leary MN, Ashe TD, La Spada AR, Kennedy BK. 2015 Aug. Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity. J Clin Invest. 125(8):2952-64. doi: 10.1172/JCI77361.
  • 5. McCormick MA, Tsai SY, Kennedy BK. 2011 Jan. TOR and ageing: a complex pathway for a complex process. Philos Trans R Soc Lond B Biol Sci. 366(1561):17-27. doi: 10.1098/rstb.2010.0198.