Sek Tong, Derrick Ong

Ong Sek Tong, Derrick

  • Assistant Professor, Department of Physiology
Joint Appointment(s)
  • Joint Principal Investigator, Institute of Molecular and Cell Biology
Academic Qualifications
  • Ph.D. (Chemical Biology), The Scripps Research Institute (CA), USA
  • PGDE (Credit), Nanyang Technological University, Singapore
  • M.S. (Biology), National University of Singapore, Singapore
  • B.S. (1st Class Honors) (Biology), National University of Singapore, Singapore
Research Interest(s)
  • Ageing
  • Brain stem cells
  • Regenerative Medicine
  • Cancer stem cells
Recent Publications
  • 1. Ong DST, Hu B, Ho YW, SauvĂ© CEG, Bristow CA, Wang Q, Multani AS, Chen P, Nezi L, Jiang S et al. 2017 Oct. PAF promotes stemness and radioresistance of glioma stem cells. Proceedings of the National Academy of Sciences of the United States of America. 114(43):E9085-E9095. doi: 10.1073/pnas.1708122114.
  • 2. Hu B, Wang Q, Wang YA, Hua S, Sauve CG, Ong DST, Lan ZD, Chang Q, Ho YW, Marchesini M, Lu X, Zhong Y, Zhang J, Deng P, Tan Z, Wang G, Liao WT, Corley LJ, Yan H, Zhang J, You Y, Liu N, Cai L, Finocchiaro G, Phillips JJ, Berger MS, Spring DJ, Hu J, Sulman EP, Fuller GN, Chin L, Verhaak RGW, DePinho RA. 2016 Nov. Epigenetic activation of WNT5A drives glioma stem cell differentiation and invasive growth. Cell. 167; 1281. doi: 10.1016/j.cell.2016.10.039.
  • 3. Colla S, Ong DST, Ogoti Y, Marchesini M, Mistry NA, Clise-Dwyer K, Ang SA, Storti P, Viale A, Giuliani N et al. 2015 Jan. Telomere Dysfunction Drives Aberrant Hematopoietic Differentiation and Myelodysplastic Syndrome. Cancer Cell. 27(5):644-657. doi: 10.1016/j.ccell.2015.04.007.