Siew Peng, Esther Wong

Wong Siew Peng, Esther

  • Research Assistant Professor, Department of Physiology
  • Research Assistant Professor, Centre for Healthy Ageing, National University Hospital
Academic Qualifications
  • PhD, National University of Singapore
Research Interest(s)
  • Autophagy
  • Proteostasis
  • Neurodegeneration and Age-related diseases
  • Mitochondrial homeostasis
  • Genomic instability
Recent Publications
  • 1. Tan SJ, Yu CY, Sim ZW, Low ZS, Lee B, See F, Min N, Gautam A, Chu JJH, Ng KW and Wong E. 2019 Jan. Pomegranate activates TFEB to promote autophagy-lysosomal fitness and mitophagy. Scientific Reports. 9:727. DOI:10.1038/s41598-018-37400-1.
  • 2. Loos B, Klionsky DJ and Wong E. 2017 Sep. Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging. Progress in Neurobiology.156: 90-106. DOI: 10.1016/j.pneurobio.2017.05.001.
  • 3. Tan SJ and Wong E. 2017 Mar. Mitophagy transcriptome: mechanistic insights into polyphenols-mediated mitophagy. Oxidative Medicine and Cellular Longevity. Vol. 2017. Article ID 9028435.
  • 4. Cuervo AM and Wong E. 2014 Jan. Chaperone-mediated autophagy: roles in disease and aging. Cell Research. 24: 92-104. DOI:10.1038/cr.2013.153.
  • 5. Wong E, Bejarano E, Rakshit M, Lee K, Hanson HH, Zaarur N, Phillips GR, Sherman MY and Cuervo AM. 2012 Dec. Molecular determinants of selective clearance of protein inclusions by autophagy. Nature Communications. 3: 1240. DOI:10.1038/ncomms2244.