Kwok Soon Wun

Wun Kwok Soon

  • Senior Research Fellow, Department of Biochemistry
Academic Qualifications
  • PhD, Monash University, Australia
  • BSc (Hons), The University of Melbourne, Australia
  • Dip Biotech, Ngee Ann Polytechnic, Singapore
Research Interest(s)
  • T cell Biology
  • Structural Biology
Recent Publications
  • 1. Wun, KS, Reijneveld, JF, Cheng, TY, Ladell, K, Uldrich, AP, Le Nours, J, Miners, KL, McLaren, JE, Grant, EJ, Haigh, OL, Watkins, TS, Suliman, S, Iwany, S, Jimenez, J, Calderon, R, Tamara, KL, Leon, SR, Murray, MB, Mayfield, JA, Altman, JD, Purcell, AW, Miles, JJ, Godfrey, DI, Gras, S, Price, DA, Van Rhijn, I, Moody, DB and Rossjohn, J. (2018) T-cell autoreactivity directed towards CD1c itself rather than carried self-lipids. Nat Immunol. 19:397-406.
  • 2. Wun KS, Ross F, Patel O, Besra GS, Porcelli SA, Richardson SK, Keshipeddy S, Howell AR, Godfrey DI, Rossjohn J. (2013) Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex. J Biol Chem. 287:39139-48.
  • 3. Wun, KS, Cameron, G, Patel, O, Pang, SS, Pellicci, DG, Sullivan, LC, Keshipeddy, S, Young, MH, Uldrich, AP, Thakur, MS, Richardson, SK, Howell, AR. Illarionov, PA, Brooks, AG, Besra, GS, McCluskey, J, Gapin, L, Porcelli, SA, Godfrey, DI and Rossjohn, J. (2011) A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells. Immunity. 34: 327-39.
  • 4. Wun, KS, Borg, NA, Kjer-Nielsen, L, Beddoe, T, Koh, R, Richardson, SK, Thakur, M, Howell, AR, Scott-Browne, JP, Gapin, L, Godfrey, DI, McCluskey, J and Rossjohn, J. (2008). A minimal binding footprint on CD1d-glycolipid is a basis for selection of human NKT TCR. J Exp Med. 205:939-49.
  • 5. Borg, NA, Wun, KS, Kjer-Nielsen, L, Wilce, MC, Pellicci, DG, Koh, R, Besra, GS, Bharadwaj, M, Godfrey, DI, McCluskey, J and Rossjohn, J. (2007). CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 448:44-49.