Guat Lay, Caroline Lee

Lee Guat Lay, Caroline

Appointment(s)
  • Associate Professor, Department of Biochemistry
  • Associate Professor, Duke-NUS Graduate Medical School
Administrative Appointment(s)
  • Supervisor, NUS Graduate School for Integrative Sciences and Engineering
  • EXCO Member, NUS Graduate School for Integrative Sciences and Engineering
  • Chairperson, Admissions Committee, NUS Graduate School for Integrative Sciences and Engineering
  • Chairperson, Teaching Excellence Award Committee, NUS Graduate School for Integrative Sciences and Engineering
Joint Appointment(s)
  • Principal Investigator, National Cancer Centre, Singapore
Academic Qualifications
  • PhD, Baylor College of Medicine, Houston, Texas, USA
  • BSc, National University of Singapore, Singapore
Research Interest(s)
  • Next-Generation Sequencing
  • Metagenomics
  • Hepatocellular Carcinoma
  • Pharmacogenomics
  • Cancer Genomics
Recent Publications
  • 1. Gao Y, Theng SS, Mah WC, Lee CG. 2015 Jul. Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity. Biol Open. 4(8):961-9. doi: 10.1242/bio.011189. 26142316.
  • 2. Xiang Y, Stine ZE, Xia J, Lu Y, O'Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CG, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV. 2015 Jun. Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. J Clin Invest. 125(6):2293-306. doi: 10.1172/JCI75836. 25915584.
  • 3. Gu J, Fu CY, Ng BK, Liu LB, Lim-Tan SK, Lee CG. 2015 May. Enhancement of early cervical cancer diagnosis with epithelial layer analysis of fluorescence lifetime images. PLoS One. 10(5):e0125706. doi: 10.1371/journal.pone.0125706. 25966026.
  • 4. Rajan-Babu IS, Law HY, Yoon CS, Lee CG, Chong SS. 2015 May. Simplified strategy for rapid first-line screening of fragile X syndrome: closed-tube triplet-primed PCR and amplicon melt peak analysis. Expert Rev Mol Med. 17:e7. doi: 10.1017/erm.2015.5. 25936533.
  • 5. Rajan-Babu IS, Teo CR, Lian M, Lee CG, Law HY, Chong SS. 2015 Mar. Single-tube methylation-specific duplex-PCR assay for rapid and accurate diagnosis of Fragile X Mental Retardation 1-related disorders. Expert Rev Mol Diagn. 15(3):431-41. doi: 10.1586/14737159.2015.1001749. 25583300.