Poh San Lai

Lai Poh San

  • Associate Professor, Department of Paediatrics
Administrative Appointment(s)
  • Deputy Chairman, NUS Institutional Biosafety Committee
  • Vice-Chair, MD1 Tahir Foundation Research Safety Commitee
  • Member, NUS Medicine Faculty Safety Committee
  • Member, Centre for Translational Medicine Safety Committee
Joint Appointment(s)
  • Adjunct Faculty, Genome Institute of Singapore, A*STAR
  • Adjunct Principal Member of Technical Staff, Defence Medical Research & Environmental Research Institutes, DSO National Laboratories
  • Member, Defence Science Organisation and Singapore Armed Forces Institutional Review Board
Academic Qualifications
  • PhD, National University of Singapore, Singapore
Research Interest(s)
  • Neuromuscular
  • Congenital
  • Next-gen Sequencing
  • NGS
  • Diagnosis
Recent Publications
  • 1. Ar Rochmah M, Awano H, Awaya T, Harahap NIF, Morisada N, Bouike Y, Saito T, Kubo Y, Saito K, Lai PS et al. 2017 Nov. Spinal muscular atrophy carriers with two SMN1 copies. Brain and Development 39(10):851-860. doi: 10.1016/j.braindev.2017.06.002.
  • 2. Ar Rochmah M, Harahap NIF, Niba ETE, Nakanishi K, Awano H, Morioka I, Iijima K, Saito T, Saito K, Lai PS et al. 2017 Oct. Genetic screening of spinal muscular atrophy using a real-time modified COP-PCR technique with dried blood-spot DNA. Brain and Development. 39(9):774-782. doi: 10.1016/j.braindev.2017.04.015.
  • 3. Takarada T, Ar Rochmah M, Harahap NIF, Shinohara M, Saito T, Saito K, Lai PS, Bouike Y, Takeshima Y, Awano H et al. 2017 Aug. SMA mutations in SMN Tudor and C-terminal domains destabilize the protein. Brain and Development 39(7):606-612. doi: 10.1016/j.braindev.2017.03.002.
  • 4. Tomar S, Sethi R, Sundar G, Thuan CQ, Boon LQ, Lai PS. 2017 Jun. Mutation spectrum of RB1 mutations in retinoblastoma cases from Singapore with implications for genetic management and counselling. PLOS One. 12(6): e0178776. doi: 10.1371/journal.pone.0178776.
  • 5. Chong A, Malavasi F, Israel S, Khord CC, Yap VB, Monakhov M, Chew SH, Lai PS, Ebstein RP. 2017 Apr. ADP ribosyl-cyclases (CD38/CD157), social skills and friendship. Psychoneuroendocrinology. 78:185-192. doi: 10.1016/j.psyneuen.2017.01.011.