Lih Wen Deng

Deng Lih Wen

Appointment(s)
  • Associate Professor, Department of Biochemistry
Administrative Appointment(s)
  • Faculty, NUS Graduate School for Integrative Sciences and Engineering
  • Affiliate, National University Cancer Institute, Singapore, National University Health System
Academic Qualifications
  • PhD, University of Cambridge, United Kingdom
  • BSc, National Taiwan University, Taiwan
Research Interest(s)
  • Genomic Instability
  • Cervical Cancer
  • Ovarian Cancer
  • Cancer Metabolism
  • Chemoradiation Resistance
Recent Publications
  • 1. Lee ZW, Deng LW. 2015. Role of H2S Donors in Cancer Biology. Handb Exp Pharmacol. 230:243-65. doi: 10.1007/978-3-319-18144-8_13. 26162839.
  • 2. Feng W, Teo XY, Novera W, Ramanujulu PM, Liang D, Huang D, Moore PK, Deng LW, Dymock BW. 2015 Aug. Discovery of new H2S releasing phosphordithioates and 2,3-dihydro-2-phenyl-2-sulfanylenebenzo[d][1,3,2]oxazaphospholes with improved antiproliferative activity. J Med Chem. 58(16):6456-80. doi: 10.1021/acs.jmedchem.5b00848. 26147240.
  • 3. Nin DS, Huang W, Ali M, Yew CW, Kutateladze TG, Deng LW. 2015 Apr. O-GlcNAcylation of MLL5β is essential for MLL5β-AP1 transcription complex assembly at the HPV16/18 Long Control Region. J Mol Cell Biol. 7(2):180-3. doi: 10.1093/jmcb/mjv009. 25670814.
  • 4. Dong Liang, Chenhui Wang, Restituto Tocmo, Haixia Wu, Lih-Wen Deng, Dejian Huang. 2015 Apr. Hydrogen sulfide (H2S) releasing capacity of essential oils isolated from organosulfur rich fruits and vegetables. Journal of Functional Foods. 14:634-640. doi: 10.1016/j.jff.2015.02.007.
  • 5. Nin DS, Yew CW, Tay SK, Deng LW. 2014 Nov. Targeted silencing of MLL5ß inhibits tumor growth and promotes gamma-irradiation sensitization in HPV16/18-associated cervical cancers. Mol Cancer Ther. 13(11):2572-82. doi: 10.1158/1535-7163.MCT-14-0019. 25172963.