Bo Xue

Xue Bo

Appointment(s)
  • Senior Research Fellow
Academic Qualifications
  • Bachelor of Engineering & Bachelor of Arts, Tianjin University
  • Master of Engineering, Tianjin University
  • PhD, Tianjin University
Research Interest(s)
  • Protein structure by X-ray crystallography
  • Rational design of enzymes
  • Protein homology modelling
Recent Publications
  • 1. Fan, J., Goh, H., Ding, K., Xue, B., Robinson, R.C., and Yang, D. (2017). Structural Basis for pH-mediated Regulation of F-actin Severing by Gelsolin Domain 1. Sci Rep 7, 45230.
  • 2. Sun, H., Yeo, W.L., Lim, Y.H., Chew, X., Smith, D.J., Xue, B., Chan, K.P., Robinson, R.C., Robins, E.G., Zhao, H., et al. (2016). Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate. Angew. Chem. Int. Ed. Engl. 55, 14277–14280.
  • 3. Xue, B., Leyrat, C., Grimes, J.M., and Robinson, R.C. (2014). Structural basis of thymosin-β4/profilin exchange leading to actin filament polymerization. Proc. Natl. Acad. Sci. U.S.A. 111, E4596-4605.
  • 4. Xue, B., Chow, J.Y., Baldansuren, A., Yap, L.L., Gan, Y.H., Dikanov, S.A., Robinson, R.C., and Yew, W.S. (2013). Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry 52, 2359–2370.
  • 5. Chow, J.Y., Xue, B., Lee, K.H., Tung, A., Wu, L., Robinson, R.C., and Yew, W.S. (2010). Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily. J. Biol. Chem. 285, 40911–40920.