Ee Sin Chen

Chen Ee Sin

  • Assistant Professor, Department of Biochemistry
Administrative Appointment(s)
  • Supervisor, NUS Graduate School for Integrative Sciences and Engineering
Academic Qualifications
  • PhD, Kyoto University, Japan
  • MSc, Kyoto University, Japan
  • BSc (Hons), National University of Singapore, Singapore
Research Interest(s)
  • Cancer
  • Epigenetics
  • Chromatin
  • Chemogenomics
  • Chemotherapeutic Drugs
  • Cell Cycle
Recent Publications
  • 1. Lim KK, Ong TY, Tan YR, Yang EG, Ren B, Seah KS, Yang Z, Tan TS, Dymock BW, Chen ES. (2015 Sep) Mutation of histone H3 serine 86 disrupts GATA factor Ams2 expression and precise chromosome segregation in fission yeast. Sci Rep. 5:14064. doi: 10.1038/srep14064. 26369364
  • 2. Tang MY, Guo H, Nguyen TT, Low LS, Jackson RA, Yamada T, Chen ES. (2015 May) Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult. Gene. 562(1):70-5. doi: 10.1016/j.gene.2015.02.041. 25701403
  • 3. Nguyen TT, Lim JS, Tang RM, Zhang L, Chen ES. (2015 Feb) Fitness profling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Sci Rep. 5:8400. doi: 10.1038/srep08400. 25669599
  • 4. Tay Z, Koo SH, Nguyen TT, Tan TS, Chen ML, Chin CF, Lim KK, Ang WH, Bay BH, Lee EJ, Chen ES. (2014) P-glycoprotein and vacuolar ATPase synergistically confer anthracycline resistance to fission yeast and human cells. Curr Med Chem. 21(2):251-60. 24059229