Leilei Chen

Chen Leilei

  • Assistant Professor, Department of Anatomy
Administrative Appointment(s)
  • Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Academic Qualifications
  • PhD, The University of Hong Kong, China
  • MD, Jiangsu University, China
Research Interest(s)
  • RNA Editing
  • Post-transcriptional Regulation
  • Cancer Biology
Recent Publications
  • 1. Song Y, Pan G, Chen L, Ma S, Zeng T, Man Chan TH, Li L, Lian Q, Chow R, Cai X, Li Y, Li Y, Liu M, Li Y, Zhu Y, Wong N, Yuan YF, Pei D, Guan XY. 2015 Oct. Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells. Gastroenterology. 149(4):1068-81.e5. doi: 10.1053/j.gastro.2015.06.010. 26099525.
  • 2. Hong H, Lin JS, Chen L. 2015 Mar. Regulatory factors governing Adenosine-to-Inosine (A-to-I) RNA editing. Biosci Rep. 31;35(2). doi: 10.1042/BSR20140190. 25662729.
  • 3. Wang J, Liu M, Chen L, Chan TH, Jiang L, Yuan YF, Guan XY. 2015 Jan. Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility. Oncotarget. 6(3):1618-30. doi: 10.18632/oncotarget.2730. 25575811.
  • 4. Qiao JJ, Chan TH, Qin YR, Chen L. 2014 Aug. ADAR1: a promising new biomarker for esophageal squamous cell carcinoma? Expert Rev Anticancer Ther. 14(8):865-8. doi: 10.1586/14737140.2014.928595. 24928581.
  • 5. Chan TH, Lin CH, Qi L, Fei J, Li Y, Yong KJ, Liu M, Song Y, Chow RK, Ng VH, Yuan YF, Tenen DG, Guan XY, Chen L. 2014 May. A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma. Gut. 63(5):832-43. doi: 10.1136/gutjnl-2012-304037. 23766440.