Guat Lay, Caroline Lee

Lee Guat Lay, Caroline

Appointment(s)
  • Associate Professor, Department of Biochemistry
  • Associate Professor, Duke-NUS Graduate Medical School
Administrative Appointment(s)
  • Supervisor, NUS Graduate School for Integrative Sciences and Engineering
  • EXCO Member, NUS Graduate School for Integrative Sciences and Engineering
  • Chairperson, Admissions Committee, NUS Graduate School for Integrative Sciences and Engineering
  • Chairperson, Teaching Excellence Award Committee, NUS Graduate School for Integrative Sciences and Engineering
Joint Appointment(s)
  • Principal Investigator, National Cancer Centre, Singapore
Academic Qualifications
  • PhD, Baylor College of Medicine, Houston, Texas, USA
  • BSc, National University of Singapore, Singapore
Research Interest(s)
  • Next-Generation Sequencing
  • Metagenomics
  • Hepatocellular Carcinoma
  • Pharmacogenomics
  • Cancer Genomics
Recent Publications
  • 1. Zhao M, Cheah FSH, Chen M, Lee CG, Law HY, Chong SS. 2017 Jul. Improved high sensitivity screen for huntington disease using a one-step triplet-primed PCR and melting curve assay. PLoS ONE. 12(7). doi: 10.1371/journal.pone.0180984.
  • 2. Lian M, Zhao M, Lee CG, Chong SS. 2017 Jun. Single-tube dodecaplex PCR panel of polymorphic microsatellite markers closely linked to the DMPK CTG repeat for preimplantation genetic diagnosis of myotonic dystrophy type 1. Clinical Chemistry. 63(6):1127-1140. doi: 10.1373/clinchem.2017.271528.
  • 3. Chan CY, Ng KH, Chen J, Lu J, Lee CGL, Tan PH, Jordan SC, He HY, Yap HK. 2016 Dec. Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in interleukin-13-induced minimal change-like nephropathy. Clinical Science. 130(24):2317-2327. doi: 10.1042/CS20160312.
  • 4. Lian M, Law HY, Lee CG, Chong SS. 2016 Nov. Defining the performance parameters of a rapid screening tool for myotonic dystrophy type 1 based on triplet-primed PCR and melt curve analysis. Expert Review of Molecular Diagnostics. 16(11):1221-1232. doi: 10.1080/14737159.2016.1241145.
  • 5. Chan C, Thurnherr T, Wang J, Gallart-Palau X, Sze SK, Rozen S, Lee CG. 2016 Oct. Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein. Molecular Oncology. 10(8):1183-1195. doi: 10.1016/j.molonc.2016.05.006.