Siong Chuan, Samuel Chong

Chong Siong Chuan, Samuel

  • Associate Professor, Department of Paediatrics
Administrative Appointment(s)
  • Scientific Advisor, Molecular Diagnosis Centre and Clinical Cytogenetics Service
  • Director, Preimplantation Genetic Diagnosis Centre, Khoo Teck Puat-National University Children's Medical Institute, National University Health System
Academic Qualifications
  • BSc (Honours), National University of Singapore, Singapore
  • MSc, University of British Columbia, Canada
  • PhD, Baylor College of Medicine, USA
Research Interest(s)
  • Preimplantation Genetic Diagnosis (PGD)
  • Thalassemia
  • Mental Retardation
  • Movement Disorders
Recent Publications
  • 1. Rajan-Babu IS, Lian M, Cheah FSH, Chen M, Tan ASC, Prasath EB, Loh SF, Chong SS. 2017 Jul. FMR1 CGG repeat expansion mutation detection and linked haplotype analysis for reliable and accurate preimplantation genetic diagnosis of fragile X syndrome. Expert Reviews in Molecular Medicine. doi: 10.1017/erm.2017.10.
  • 2. Zhao M, Chen M, Tan ASC, Cheah FSH, Mathew J, Wong PC, Chong SS. 2017 Jul. Single-tube tetradecaplex panel of highly polymorphic microsatellite markers < 1 Mb from F8 for simplified preimplantation genetic diagnosis of hemophilia A. Journal of Thrombosis and Haemostasis. 15(7):1473-1483. doi: 10.1111/jth.13685.
  • 3. Zhao M, Cheah FSH, Chen M, Lee CG, Law HY, Chong SS. 2017 Jul. Improved high sensitivity screen for huntington disease using a one-step triplet-primed PCR and melting curve assay. PLoS ONE. 12(7). doi: 10.1371/journal.pone.0180984.
  • 4. Lian M, Zhao M, Lee CG, Chong SS. 2017 Jun. Single-tube dodecaplex PCR panel of polymorphic microsatellite markers closely linked to the DMPK CTG repeat for preimplantation genetic diagnosis of myotonic dystrophy type 1. Clinical Chemistry. 63(6):1127-1140. doi: 10.1373/clinchem.2017.271528.
  • 5. Lim GXY, Yeo M, Koh YY, Winarni TI, Rajan-Babu IS, Chong SS, Faradz SMH, Guan M. 2017 Mar. Validation of a commercially available test that enables the quantification of the numbers of CGG trinucleotide repeat expansion in FMR1 gene. PLoS ONE. 12(3). doi: 10.1371/journal.pone.0180984.