Soon-U, Lawrence Lee

Lee Soon-U, Lawrence

  • Assistant Professor, Department of Medicine
  • Consultant, Division of Infectious Disease, University Medicine Cluster, National University Health System
Joint Appointment(s)
  • Visiting Consultant, Department of Infectious Disease, Tan Tock Seng Hospital / Institute of Infectious Diseases and Epidemiology
  • Visiting Consultant, Clinical Trials and Research Unit, Changi General Hospital
Academic Qualifications
  • PhD, Johns Hopkins University School of Public Health, USA
  • MRCP, Royal College of Physicians, United Kingdom
  • BSc, University of New South Wales, Australia
  • MBBS (Hons, First Class), University of New South Wales, Australia   
Research Interest(s)
  • Tuberculosis
  • HIV
  • Pharmacokinetics
  • Analytical Chemistry
  • Therapeutic Drug Monitoring
  • Clinical Pharmacology
Recent Publications
  • 1. Gurumurthy M, Verma R, Naftalin CM, Hee KH, Lu Q, Tan KH, Issac S, Lin W, Tan A, Seng K-Y et al. 2017 Jul. Activity of faropenem with and without rifampicin against Mycobacterium tuberculosis: evaluation in a whole-blood bactericidal activity trial. Journal of Antimicrobial Chemotherapy. 72(7):2012-2019. doi: 10.1093/jac/dkx081.
  • 2. Hee KH, Leaw YKJ, Ong JL, Lee LS. 2017 Jun. Development and validation of liquid chromatography tandem mass spectrometry method quantitative determination of polymyxin B1, polymyxin B2, polymyxin B3 and isoleucine-polymyxin B1 in human plasma and its application in clinical studies. Journal of Pharmaceutical and Biomedical Analysis. 140:91-97. doi: 10.1016/j.jpba.2017.03.018.
  • 3. Lee LSU. 2017 Apr. Infectious diseases in Singapore and Asia: Persistent challenges in a new era. Singapore Medical Journal. 58(4):169-170. doi: 10.11622/smedj.2017025.
  • 4. Wang L, Chan CEL, Wong ALA, Wong FC, Lim SW, Chinnathambi A, Alharbi SA, Lee LSU, Soo R, Yong WP et al. 2017 Jan. Combined use of irinotecan with histone deacetylase inhibitor belinostat could cause severe toxicity by inhibiting SN-38 glucuronidation via UGT1A1. Oncotarget. 8(25):41572-41581. doi: 10.18632/oncotarget.15017.
  • 5. Lim TP, Hee DKH, Lee W, Teo JQM, Cai Y, Chia SYH, Leaw JYK, Lee SJY, Lee LSU, Kwa AL. 2016 Sep. Physicochemical Stability Study of Polymyxin B in Various Infusion Solutions for Administration to Critically Ill Patients. Annals of Pharmacotherapy. 50(9):790-792. doi: 10.1177/1060028016649598.